Evidence map›Paper›PMID 36596447›Full record

ArticleThrombosis and haemostasis2023

Longitudinal In Vivo Monitoring of Atheroprogression in Hypercholesterolemic Mice Using Photoacoustic Imaging.

Bartolo Ferraro, Pierangela Giustetto, Olga Schengel, Ludwig T Weckbach, Lars Maegdefessel, Oliver Soehnlein

Abstract read
In one paragraph

Article in Thrombosis and haemostasis, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Mouse Cardiovascular Imaging.Current protocols · 2024
    Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Bartolo FerraroInstitute for Cardiovascular Prevention (IPEK), LMU Munich, Munich, Germany.
Pierangela GiustettoFujifilm VisualSonics Consultant, Amsterdam, The Netherlands.
Olga SchengelInstitute for Experimental Pathology (ExPat), Centre for Molecular Biology of Inflammation (ZMBE), University of Münster, Münster, Germany.
Ludwig T WeckbachDZHK, Partner Site Munich Heart Alliance, Munich, Germany.
Lars MaegdefesselDZHK, Partner Site Munich Heart Alliance, Munich, Germany.
Oliver SoehnleinInstitute for Cardiovascular Prevention (IPEK), LMU Munich, Munich, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

aimThe ability to recognize and monitor atherosclerotic lesion development using noninvasive imaging is crucial in preventive cardiology. The aim of the present study was to establish a protocol for longitudinal monitoring of plaque lipid, collagen, and macrophage burden as well as of endothelial permeability. METHODS AND

resultsPhotoacoustic signals derived from endogenous or exogenous dyes assessed in vivo, in plaques of albino

conclusionsThe present study shows an innovative approach to assess arterial inflammation in a non-invasive fashion, applicable to longitudinal analyses of changes of atherosclerotic lesion composition. Such approach could prove important in the preclinical testing of therapeutic interventions in mice carrying pre-established lesions.

Indexed as

AtherosclerosisPhotoacoustic TechniquesPlaque, AtheroscleroticAnimalsApolipoproteins EDiagnostic ImagingMacrophagesMiceMice, KnockoutApolipoproteins E

Identifiers

PMID36596447
PMCPMC10113035

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.