Evidence map›Paper›PMID 36595928›Full record

ArticleSTAR protocols2022

Software for segmenting and quantifying calcium signals using multi-scale generative adversarial networks.

Hussein Moghnieh, Sharif Amit Kamran, Khondker Fariha Hossain, Nyanbol Kuol, Sarah Riar, Allison Bartlett, Alireza Tavakkoli, Salah A Baker

Abstract read
In one paragraph

Article in STAR protocols, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Hussein MoghniehDepartment of Electrical and Computer Engineering, McGill University, Montréal, QC H3A 0E9, Canada.
Sharif Amit KamranDepartment of Physiology and Cell Biology, University of Nevada, School of Medicine, Anderson Medical Building MS352, Reno, NV 89557, USA; Department of Computer Science and Engineering, University of Nevada, Reno, NV 89557, USA.
Khondker Fariha HossainDepartment of Computer Science and Engineering, University of Nevada, Reno, NV 89557, USA.
Nyanbol KuolDepartment of Physiology and Cell Biology, University of Nevada, School of Medicine, Anderson Medical Building MS352, Reno, NV 89557, USA.
Sarah RiarDepartment of Physiology and Cell Biology, University of Nevada, School of Medicine, Anderson Medical Building MS352, Reno, NV 89557, USA.
Allison BartlettDepartment of Physiology and Cell Biology, University of Nevada, School of Medicine, Anderson Medical Building MS352, Reno, NV 89557, USA.
Alireza TavakkoliDepartment of Computer Science and Engineering, University of Nevada, Reno, NV 89557, USA.
Salah A BakerDepartment of Physiology and Cell Biology, University of Nevada, School of Medicine, Anderson Medical Building MS352, Reno, NV 89557, USA. Electronic address: sabubaker@med.unr.edu.

Funding

Role of interstitial cells of Cajal in patterned colonic motor activityR01DK120759 · NIDDK · UNIVERSITY OF NEVADA RENO · PI Sal Baker, KENTON M SANDERS · 2019 to 2026
$3.4M
6 · The paper itself

Abstract

Cellular calcium fluorescence imaging utilized to study cellular behaviors typically results in large datasets and a profound need for standardized and accurate analysis methods. Here, we describe open-source software (4SM) to overcome these limitations using an automated machine learning pipeline for subcellular calcium signal segmentation of spatiotemporal maps. The primary use of 4SM is to analyze spatiotemporal maps of calcium activities within cells or across multiple cells. For complete details on the use and execution of this protocol, please refer to Kamran et al. (2022).

Indexed as

CalciumNeural Networks, ComputerImage Processing, Computer-AssistedMachine LearningSoftwareCalciumCell BiologyComputer sciencesMicroscopy

Identifiers

PMID36595928
PMCPMC9674926

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.