ArticleThe American psychologist2022
Brain-body pathways linking racism and health.
Article in The American psychologist, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.
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Who cites it
27 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Inflammation as a mediating pathway between social defeat and mental health in humans: A systematic review.Translational psychiatry · 2026Pooled it
- Racism and alterations in brain structure and function: A narrative review of emerging neuroimaging evidence in racialized individuals.Cognitive, affective & behavioral neuroscience · 2026Review
- Examining the Social and Mental Health Benefits of Ethnic Studies and DEI among BIPOCs and Whites.Journal of racial and ethnic health disparities · 2026Article
- Adverse policing as a social exposome pathway: Implications for depression, cognition, and dementia risk.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Article
- Multivariate environmental exposures are reflected in whole-brain functional connectivity and cognition in youth.Developmental cognitive neuroscience · 2026Article
- The Burden of Witnessing: The Impact of Vicarious Experiences of Racism & Anti-Immigrant Discrimination on Healthcare Utilization.Journal of racial and ethnic health disparities · 2026Article
- Impact of Allostatic Load on Overall Survival in Patients With Endometrial Cancer.Cancer medicine · 2026Article
- Classism, Perceived Stress, and Mental Health Symptoms: Cross-Sectional Evidence from a Census-Matched U.S. Sample.Healthcare (Basel, Switzerland) · 2026Article
- Perceived Racism, Brain Development, and Internalizing and Externalizing Symptoms: Findings From the ABCD Study.Journal of the American Academy of Child and Adolescent Psychiatry · 2026Article
- Cardiometabolic risk mediates the association between perceived stress and learning and memory similarly among Hispanic/Latino and non-Hispanic White individuals.Journal of clinical and experimental neuropsychology · 2026Observational
- A review of the impact of structural racism on lived experiences of adolescents of African descent: Implications for development, brain structure, and health.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026Review
- Lived experiences and perspectives of persons with conditions marked by autonomic dysfunction.PloS one · 2026Article
- The relationship between racial discrimination and white matter among Black older adults.Neurobiology of aging · 2025Article
- Contemplative Practices as a Form of Stress Management for Patients with Kidney Disease.Clinical journal of the American Society of Nephrology : CJASN · 2025Review
- Multivariate environmental exposures are reflected in whole-brain functional connectivity and cognition in youth.bioRxiv : the preprint server for biology · 2025Article
- Discrimination and wellbeing are differentially related to pain severity for the racially marginalized.Pain medicine (Malden, Mass.) · 2025Article
- Multilevel Racism and Discrimination and Cardiovascular Disease and Related Biopsychosocial Mechanisms: An Integrated Scoping and Literature Review and Future Research Agenda.Current cardiology reports · 2025Article
- Extremism, racism and riots: exploring the political, social and cultural determinants of poor mental health.BJPsych open · 2024Article
- Health Care Discrimination Affects Patient Activation, Communication Self-Efficacy, and Pain for Black Americans.The journal of pain · 2024Article
- Influences of sex and gender on the associations between risk and protective factors, brain, and behavior.Biology of sex differences · 2024Review
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
Racial disparities in health are a major public health problem in the United States, especially when comparing chronic disease morbidity and mortality for Black versus White Americans. These health disparities are primarily due to insidious anti-Black racism that permeates American history, current culture and institutions, and interpersonal interactions. But how does racism get under the skull and the skin to influence brain and bodily processes that impact the health of Black Americans? In the present article, we present a model describing the possible neural and inflammatory mechanisms linking racism and health. We hypothesize that racism influences neural activity and connectivity in the salience and default mode networks of the brain and disrupts interactions between these networks and the executive control network. This pattern of neural functioning in turn leads to greater sympathetic nervous system signaling, hypothalamic-pituitary-adrenal axis activation, and increased expression of genes involved in inflammation, ultimately leading to higher levels of proinflammatory cytokines in the body and brain. Over time, these neural and physiological responses can lead to chronic physical and mental health conditions, disrupt well-being, and cause premature mortality. Given that research in this area is underdeveloped to date, we emphasize opportunities for future research that are needed to build a comprehensive mechanistic understanding of the brain-body pathways linking anti-Black racism and health. (PsycInfo Database Record (c) 2023 APA, all rights reserved).
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