Evidence map›Paper›PMID 36595063›Full record

ReviewMammalian genome : official journal of the International Mammalian Genome Society2023

Three-dimensional microCT imaging of mouse heart development from early post-implantation to late fetal stages.

Nanbing Li-Villarreal, Tara L Rasmussen, Audrey E Christiansen, Mary E Dickinson, Chih-Wei Hsu

Abstract readReview
In one paragraph

Review in Mammalian genome : official journal of the International Mammalian Genome Society, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Mouse Cardiovascular Imaging.Current protocols · 2024
    Review
  5. Imaging Approaches and the Quantitative Analysis of Heart Development.Journal of cardiovascular development and disease · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Nanbing Li-Villarreal *Department of Integrative Physiology, Baylor College of Medicine, One Baylor Plaza, Houston, TX, 77030, USA.ORCID 0000-0002-0688-7197
Tara L Rasmussen *Department of Integrative Physiology, Baylor College of Medicine, One Baylor Plaza, Houston, TX, 77030, USA.ORCID 0000-0003-0481-8734
Audrey E ChristiansenDepartment of Integrative Physiology, Baylor College of Medicine, One Baylor Plaza, Houston, TX, 77030, USA.ORCID 0000-0002-4918-7609
Mary E DickinsonDepartment of Integrative Physiology, Baylor College of Medicine, One Baylor Plaza, Houston, TX, 77030, USA.ORCID 0000-0003-4372-9638
Chih-Wei HsuDepartment of Integrative Physiology, Baylor College of Medicine, One Baylor Plaza, Houston, TX, 77030, USA. loganh@bcm.edu.ORCID 0000-0002-9591-9567

Funding

UM1HG006348: Cas9 Genome Integrity Supplemental ProposalUM1HG006348 · NHGRI · BAYLOR COLLEGE OF MEDICINE · PI Jason D. Heaney, Chih-Wei Logan Hsu · 2016 to 2026
$47.5M
Dynamic regulation of embryonic endothelial cell migration in response to hemodynamic forceR01HD099026 · NICHD · BAYLOR COLLEGE OF MEDICINE · PI DICKINSON, MARY E · 2019 to 2023
$2.5M
NHGRI NIH HHS UM1 HG006348NICHD NIH HHS R01 HD099026
6 · The paper itself

Abstract

Comprehensive detailed characterization of new mouse models can be challenging due to the individual focus involved in developing these models. Often models are engineered to test a specific hypothesis in a limited number of tissues, stages, and/or other contexts. Whether or not the model produces the desired phenotypes, phenotyping beyond the desired context can be extremely work intensive and these studies are often not undertaken. However, the general information resulting from broader phenotyping can be invaluable to the wider scientific community. The International Mouse Phenotyping Consortium (IMPC) and its subsidiaries, like the Knockout Mouse Project (KOMP), has made great strides in streamlining this process. In particular, the use of microCT has been an invaluable resource in examining internal organ systems throughout fetal/developmental stages. Here, we provide several novel vignettes demonstrating the utility of microCT in uncovering cardiac phenotypes both based on human disease correlations and those that are unpredicted.

Indexed as

Embryo ImplantationOrganogenesisAnimalsHumansImaging, Three-DimensionalMiceMice, KnockoutPhenotypeX-Ray Microtomography

Identifiers

PMID36595063
PMCPMC10290591

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.