ArticleJournal of cancer research and clinical oncology2023
Dual-layer spectral detector CT (SDCT) can improve the detection of mixed ground-glass lung nodules.
Article in Journal of cancer research and clinical oncology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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10 citing papers in PubMed.
- Preoperative predicting invasiveness of lung adenocarcinoma manifesting as ground-glass nodules based on multimodal images of dual-layer spectral detector CT radiomics models.Journal of cancer research and clinical oncology · 2023Trial
- Clinical Utility of Dual-Energy CT for Detection, Characterization, and Staging of Lung Tumors: A Rapid Review.Diagnostics (Basel, Switzerland) · 2026Review
- Improved interobserver agreement for perihematomal edema measurement using dual-layer spectral CT electron density imaging in intracerebral hemorrhage.Emergency radiology · 2026Article
- Predictive value of CT target scan-based radiomics and clinical features for patients with chronic obstructive pulmonary disease combined with malignant pulmonary nodules.Biomedical engineering online · 2026Article
- Dual-layer spectral detector CT electron density imaging: impressive technology for imaging characteristics of ground-glass nodules.Quantitative imaging in medicine and surgery · 2025Article
- Quantitative parameters of HRCT target scan to predict the risk of lung adenocarcinoma based on the detection of lung ground-glass nodules.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2025Article
- Dual-layer spectral detector computed tomography multiparameter machine learning model for prediction of invasive lung adenocarcinoma.Translational lung cancer research · 2025Article
- Predictive value of spectral dual-detector computed tomography forQuantitative imaging in medicine and surgery · 2024Article
- CT-based radiomics and clinical characteristics for predicting bone metastasis in lung adenocarcinoma patients.Translational lung cancer research · 2024Article
- Spectral Dual-Layer Computed Tomography Can Predict the Invasiveness of Ground-Glass Nodules: A Diagnostic Model Combined with Thymidine Kinase-1.Journal of clinical medicine · 2023Article
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6 authors.
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Abstract
backgroundMixed ground-glass lung nodules are a high-risk factor for lung adenocarcinoma. This study aimed to analyze the value of SDCT electron density imaging in the detection of mixed ground-glass lung nodules (GGNs).
method150 patients with GGNs confirmed by chest SDCT and surgical pathology were retrospectively analyzed. GGNs were screened by two senior radiologists by the double-blind method based on conventional CT and SDCT electron density images. Average CT values and electron density (ED) values of GGNs were measured for all, solid and ground-glass.
resultThirty pGGN cases determined by conventional CT were found to be mGGN on electron density images, including 23 in the invasive adenocarcinoma group (detection rate of 35.38%), which was significantly higher than that of the PGL group (14.89%, P < 0.05). In electron density images, average CT values and ED values in the PGL and invasive adenocarcinoma groups with pGGNs were no difference. The average CT value and ED value were significantly higher in the mGGN invasive adenocarcinoma group compared with the PGL group (P < 0.05). Meanwhile, ROC curve analysis of average CT value and ED value revealed AUC values for mGGN infiltration of 0.759 and 0.752.
conclusionSDCT can improve GGN visualization and increase the detection rate of mGGN compared with conventional CT. Attention should be paid to invasive adenocarcinoma for lung GGNs detected as mGGNs with high average CT value or ED value.
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