Evidence map›Paper›PMID 36594750›Full record

ArticleCurrent protocols2023

Humanization of the Shark V

Yi-Fan Zhang, Yaping Sun, Jessica Hong, Mitchell Ho

Open access · greenAbstract read
In one paragraph

Article in Current protocols, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Yi-Fan ZhangLaboratory of Molecular Biology, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland.
Yaping SunAntibody Engineering Program, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland.
Jessica HongLaboratory of Molecular Biology, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland.
Mitchell HoLaboratory of Molecular Biology, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland.
National Cancer Institute · US

Funding

Development of new antibody-based cancer therapiesZIABC010891 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI HO, MITCHELL · 2009 to 2025
$21.4M
Antibody Engineering ProgramZICBC011891 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI HO, MITCHELL · 2019 to 2025
$4.5M
Antibody Therapy of CancerZ01BC010891 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI HO, MITCHELL · 2008 to 2008
$56k
Intramural NIH HHS Z01 BC010891Intramural NIH HHS Z99 CA999999Intramural NIH HHS ZIA BC010891Intramural NIH HHS ZIC BC011891
6 · The paper itself

Abstract

The variable domain of the new antigen receptor (V

Indexed as

SharksSingle-Domain AntibodiesAnimalsAntigensComplementarity Determining RegionsHumansMammalsReceptors, AntigenAntigensComplementarity Determining RegionsReceptors, AntigenSingle-Domain AntibodiesAlphafold modelCDR graftinghumanizationshark VNAR antigen contacting residuesshark VNAR CDRshark VNAR single domain antibody

Identifiers

PMID36594750
PMCPMC9813873
OpenAlexW4313532517

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.