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ArticleInterventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences2025

The effect of the size of the new contour neurovascular device for altering intraaneurysmal flow.

Mariya S Pravdivtseva, Andrey N Pravdivtsev, Sönke Peters, Johannes Hensler, Naomi Larsen, Jan-Bernd Hövener, Olav Jansen, Fritz Wodarg

Abstract read
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Article in Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Mariya S PravdivtsevaDepartment of Radiology and Neuroradiology, Section Biomedical Imaging, Molecular Imaging North Competence Center (MOIN CC), University Medical Center Schleswig-Holstein (UKSH), Kiel University, Kiel, Germany.ORCID 0000-0001-9442-088X
Andrey N PravdivtsevDepartment of Radiology and Neuroradiology, Section Biomedical Imaging, Molecular Imaging North Competence Center (MOIN CC), University Medical Center Schleswig-Holstein (UKSH), Kiel University, Kiel, Germany.
Sönke PetersDepartment of Radiology and Neuroradiology, University Medical Center Schleswig-Holstein (UKSH), Kiel, Germany.
Johannes HenslerDepartment of Radiology and Neuroradiology, University Medical Center Schleswig-Holstein (UKSH), Kiel, Germany.ORCID 0000-0002-6594-5334
Naomi LarsenDepartment of Radiology and Neuroradiology, University Medical Center Schleswig-Holstein (UKSH), Kiel, Germany.
Jan-Bernd HövenerDepartment of Radiology and Neuroradiology, Section Biomedical Imaging, Molecular Imaging North Competence Center (MOIN CC), University Medical Center Schleswig-Holstein (UKSH), Kiel University, Kiel, Germany.
Olav JansenDepartment of Radiology and Neuroradiology, University Medical Center Schleswig-Holstein (UKSH), Kiel, Germany.
Fritz WodargDepartment of Radiology and Neuroradiology, University Medical Center Schleswig-Holstein (UKSH), Kiel, Germany.ORCID 0000-0003-1413-2699

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRecently, a novel intrasaccular device (contour neurovascular system, contour) was introduced to treat intracranial aneurysms. Contour is placed at thе aneurysm neck and reduces the intraaneurysmal blood inflow. Contour comes in a range of sizes to target different aneurysms. The efficiency of altering flow with contour and the effect of device size have not yet been investigated. Therefore, we studied the effect of the device size with patient-based aneurysm models using 2D digital subtraction angiography (DSA).

methodsThree patient-based aneurysm models with necks ranging from 2.7 to 9.7 mm were produced, providing standardized testing conditions. Contours with diameters of 5, 11, and 14 mm were implanted into the models, four of each size. 2D DSA images were acquired before and after implanting contour (15 frames/s, manual contrast injection). After injecting angiographic contrast agent, the DSA signal was recorded over time to calculate the contrast washout time (WOT), which is a measure of flow diversion efficiency.

resultsAll contour devices caused contrast agent stasis and increased WOT in aneurysm sac (

conclusionThe 5-mm contour showed the longest WOT value in our study, while no apparent difference between 11-mm contour and 14-mm contour was found.

Indexed as

Embolization, TherapeuticEndovascular ProceduresIntracranial AneurysmAngiography, Digital SubtractionCerebral AngiographyContrast MediaEquipment DesignHumansContrast Media3D printingcontour neurovascular systemDigital subtraction angiographyflow modulationintracranial aneurysm

Identifiers

PMID36594503
PMCPMC11833893

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.