ArticleAnnals of medicine2023
Analysis of prescription status of antihypertensive drugs in Chinese patients with hypertension based on real-world study.
Article in Annals of medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 12 citations in OpenAlex.
- Article
- Longitudinal associations between treatment adherence patterns and blood pressure control among rural hypertensive patients in Central China: a real-world retrospective cohort study.Frontiers in medicine · 2026Article
- Comparative effectiveness of angiotensin-converting enzyme inhibitors and angiotensin II receptor blockers on cardiovascular outcomes in older adults with type 2 diabetes mellitus: a target trial emulation study.Cardiovascular diabetology · 2025Article
- Optimizing hypertension management in China: care cascade insights and individual determinants from a national survey.Current medical research and opinion · 2025Article
- Prescribing characteristics and guideline concordance of antihypertensive western and Chinese patent medicine in Internet hospitals in China: a cross-sectional study.Frontiers in pharmacology · 2025Article
- Trends in Antihypertensive Drug Use and Irrational Prescriptions Among Elderly Patients in China (2016-2023): A Nationwide Multi-Center Cross-Sectional Survey Study.Drug design, development and therapy · 2025Article
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Authors and funding
4 authors at 1 institution in 1 country.
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Abstract
backgroundGlobally, the prevalence of hypertension and the accompanying burden of cardiovascular disease are increasing. Through drug utilization research, we can understand the prescription status of hypertension patients and promote rational drug use. The purpose of this retrospective study was to describe the current prescription pattern of antihypertensive drugs in Chinese patients and determine the compliance level of treatment guidelines. MATERIALS AND
methodsAround 11.1 million patients who received a prescription for antihypertensive therapy between January 2021 to December 2021 were obtained from a database of Hangzhou Kang Sheng Health Consulting CO., Ltd.
resultsThe mean age of hypertensive patients was 54.75 ± 12.98 years. About 6.7 million (60.30%) were males. About 46.07% of patients had comorbidities. The most common classes of antihypertensive medications used were calcium channel blockers (CCBs) and angiotensin II receptor blockers (ARBs). Around 78.33% of participants were on monotherapy. Diuretics + ARBs and Diuretics + CCBs + ARBs were the most commonly prescribed pattern in two-drug combination therapy and three-drug combination therapy, respectively.
conclusionsCCBs and ARBs were the two most frequently prescribed for patients with hypertension. The prescription pattern of antihypertensive medications in the study largely complied with recommended Chinese hypertension guidelines.Key messagesCardiovascular disease is the most common complication of hypertension.Calcium channel blockers (CCBs) and angiotensin II receptor blockers (ARBs) are the two most commonly used drugs for hypertension patients in China.The proportion of combination prescription pattern in Chinese hypertensive patients is low.
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