ArticleiScience2023
Ultra-sensitive terahertz metamaterials biosensor based on luxuriant gaps structure.
Article in iScience, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- Highly Sensitive Detection and Discrimination of Cell Suspension Based on a Metamaterials-Based Biosensor Chip.Biosensors · 2026Article
- Coherent detection of pulsed terahertz waves in solid, gaseous, and liquid media.Fundamental research · 2025Review
- Article
- Detection of In Vivo-like Cells by a Biosensor Chip Based on Metamaterials in Terahertz Regime.Biosensors · 2024Article
- A Liquid Crystal-Modulated Metastructure Sensor for Biosensing.Sensors (Basel, Switzerland) · 2023Article
- Developing a Novel Terahertz Fabry-Perot Microcavity Biosensor by Incorporating Porous Film for Yeast Sensing.Sensors (Basel, Switzerland) · 2023Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Fast, simple, and label-free detections and distinctions are desirable in cell biology analysis and diagnosis. Here, a biosensor based on terahertz metamaterial has luxuriant gaps, which can excite dipole resonance is designed. Filling the gaps with various analytes can change the biosensor's capacitance resulting in electromagnetic properties changing. The idea is verified by simulations and experiments. The theoretical sensitivity of the biosensor approaches 290 GHz/RIU, and the experimental concentration sensitivity of the biosensor is ≥ 275 kHz mL/cell. Candida Albicans, Escherichia Coli, and Shigella Dysenteriae were selected as analytes, and the measurement frequency shift is 270 GHz, 290 GHz, and 310 GHz, respectively, which indicates that the biosensor can detect and distinguish these bacteria. Successfully detection of low-concentration glioblastoma (200 cells/mL), showing great potential for the early diagnosis of glioblastoma of the biosensor. This biosensor supplies a new horizon for cell detection, which will significantly benefit cell biology investigation.
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Registered trials
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