Evidence map›Paper›PMID 36594036›Full record

ArticleiScience2023

Rapid development of motion-streak coding in the mouse visual cortex.

Manavu Tohmi, Jianhua Cang

Open access · goldAbstract read
In one paragraph

Article in iScience, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Manavu TohmiDepartment of Biology, University of Virginia, Charlottesville, VA 22904, USA.
Jianhua CangDepartment of Biology, University of Virginia, Charlottesville, VA 22904, USA.
University of Virginia · US

Funding

Neural Mechanisms of Stereoscopic VisionR01EY020950 · NEI · UNIVERSITY OF VIRGINIA · PI Jianhua Cang · 2010 to 2026
$5.9M
Visual Signal Transformation in the Retinocollicular PathwayR01EY026286 · NEI · UNIVERSITY OF VIRGINIA · PI Jianhua Cang · 2016 to 2026
$4.4M
NEI NIH HHS R01 EY020950
6 · The paper itself

Abstract

Despite its importance, the development of higher visual areas (HVAs) at the cellular resolution remains largely unknown. Here, we conducted 2-photon calcium imaging of mouse HVAs lateromedial (LM) and anterolateral (AL) and V1 to observe developmental changes in visual response properties. HVA neurons showed selectivity for orientations and directions similar to V1 neurons at eye opening, which became sharper in the following weeks. Neurons in all areas over all developmental stages tended to respond selectively to dots moving along an axis perpendicular to their preferred orientation at slow speeds, suggesting a certain level of conventional motion coding already at eye opening. In contrast, at high speeds, many neurons responded to dots moving along the axis parallel to the preferred orientation in older animals but rarely after eye opening, indicating a lack of motion-streak coding in the earlier stage. Together, our results uncover the development of visual properties in HVAs.

Indexed as

Biological sciencesDevelopmental neuroscienceNeuroscienceSensory neuroscience

Identifiers

PMID36594036
PMCPMC9804142
OpenAlexW4310927664

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.