Evidence map›Paper›PMID 36593949›Full record

ArticleTheranostics2023

Polymeric microneedles enable simultaneous delivery of cancer immunomodulatory drugs and detection of skin biomarkers.

Pere Dosta, Núria Puigmal, Alexander M Cryer, Alma L Rodríguez, Ella Scott, Ralph Weissleder, Miles A Miller, Natalie Artzi

Open access · goldAbstract read
In one paragraph

Article in Theranostics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 2 pooled it
4.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 2 syntheses or guidelines pooled it, 59 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Article
  5. Review
  6. Article
  7. Review
  8. Review
  9. Review
  10. Microneedles at the Forefront of Next Generation Theranostics.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Review
  11. Article
  12. Review
  13. Article
  14. Review
  15. Research Progress of Hydrogel Microneedles in Wound Management.ACS biomaterials science & engineering · 2024
    Review
  16. Article
  17. Review
  18. Stimulation of fracture mineralization by salt-inducible kinase inhibitors.Frontiers in bioengineering and biotechnology · 2024
    Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Pere DostaInstitute for Medical Engineering and Science (IMES), Massachusetts Institute of Technology, Cambridge, MA 02139.
Núria PuigmalInstitute for Medical Engineering and Science (IMES), Massachusetts Institute of Technology, Cambridge, MA 02139.
Alexander M CryerInstitute for Medical Engineering and Science (IMES), Massachusetts Institute of Technology, Cambridge, MA 02139.
Alma L RodríguezInstitute for Medical Engineering and Science (IMES), Massachusetts Institute of Technology, Cambridge, MA 02139.
Ella ScottCenter for Systems Biology, Massachusetts General Hospital Research Institute, Boston, MA 02114.
Ralph WeisslederCenter for Systems Biology, Massachusetts General Hospital Research Institute, Boston, MA 02114.
Miles A MillerCenter for Systems Biology, Massachusetts General Hospital Research Institute, Boston, MA 02114.
Natalie ArtziInstitute for Medical Engineering and Science (IMES), Massachusetts Institute of Technology, Cambridge, MA 02139.
Center for Systems Biology · USMassachusetts General Hospital · US

Funding

Imaging of nanotherapeutic drug actionU01CA206997 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI WEISSLEDER, MD, PHD, RALPH · 2017 to 2021
$2.9M
Dissection of in situ myeloid signaling using image-guided synthetic controlDP2CA259675 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI MILLER, MILES A · 2020 to 2023
$2.7M
NCI NIH HHS DP2 CA259675NCI NIH HHS U01 CA206997
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Immunomodulating AgentsNeoplasmsAdministration, CutaneousAnimalsDrug Delivery SystemsMicePolymersSkinTumor MicroenvironmentImmunomodulating AgentsPolymerscancerimmunotherapymicroneedlespoly(beta-amino ester)stheranostics

Identifiers

PMID36593949
PMCPMC9800729
OpenAlexW4310809970

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.