Evidence map›Paper›PMID 36593809›Full record

ArticleAnnals of gastroenterology

Substance abuse and inpatient outcomes in inflammatory bowel disease hospitalizations in the United States: a propensity matched analysis.

Pratik Patel, Hassam Ali, Swethaa Manickam, Rahul Pamarthy, Karina Fatakhova, Ramona Rajapakse

Abstract read
In one paragraph

Article in Annals of gastroenterology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Pratik PatelDepartment of Gastroenterology, Mather Hospital/Hofstra University Zucker School of Medicine, New York (Pratik Patel, Karina Fatakhova, Ramona Rajapakse).
Hassam AliDepartment of Internal Medicine, East Carolina University/Vidant Medical Center, Greenville, North Carolina (Hassam Ali, Swethaa Manickam, Rahul Pamarthy).
Swethaa ManickamDepartment of Internal Medicine, East Carolina University/Vidant Medical Center, Greenville, North Carolina (Hassam Ali, Swethaa Manickam, Rahul Pamarthy).
Rahul PamarthyDepartment of Internal Medicine, East Carolina University/Vidant Medical Center, Greenville, North Carolina (Hassam Ali, Swethaa Manickam, Rahul Pamarthy).
Karina FatakhovaDepartment of Gastroenterology, Mather Hospital/Hofstra University Zucker School of Medicine, New York (Pratik Patel, Karina Fatakhova, Ramona Rajapakse).
Ramona RajapakseDepartment of Gastroenterology, Mather Hospital/Hofstra University Zucker School of Medicine, New York (Pratik Patel, Karina Fatakhova, Ramona Rajapakse).

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Inflammatory bowel disease (IBD) is a chronic intestinal inflammation resulting in a genetically susceptible population. The present study aimed to look at the effect of substance abuse on IBD hospitalizations in the United States. Methods: We identified primary IBD hospitalizations with substance abuse using the National Inpatient Sample database (2016-2019). A matched comparison cohort of IBD hospitalizations without substance abuse was identified by 1:N propensity score matching using the nearest-neighbor method, based on demographics, hospital-level factors, and comorbidities. Results: We matched 4437 IBD hospitalizations with a diagnosis of substance abuse to 4528 hospitalizations without abuse. The median age was higher in the substance abuse group than no abuse (44 vs. 38 years, P<0.001). There was a higher prevalence of discharge to care facilities (2.9% vs. 2.2%) and against medical advice (4.9% vs. 1.8%) in the substance abuse group compared to the no abuse (P<0.001). The median length of hospital stays (LOS) (P=0.74) and hospitalization charge did not differ significantly (P=0.57). There was no significant difference in 30-day inpatient mortality among cohorts (adjusted hazard ratio 0.74, 95% confidence interval 0.32-1.81; P=0.54). There was a higher prevalence of psychoses (2.5% vs. 1.3%) and depression (18.8% vs. 15.7%) in IBD hospitalizations with substance abuse compared to those without abuse (P<0.001). Conclusions: This study reports no difference in median LOS, hospitalization charge, or mortality risk in IBD hospitalizations based on substance abuse. There is a higher prevalence of psychoses and depression in IBD patients, requiring screening for substance abuse to improve overall outcomes.

Indexed as

alcoholismInflammatory bowel diseaselength of stayNational Inpatient Sample databasesubstance-related disorders

Identifiers

PMID36593809
PMCPMC9756027

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.