Evidence map›Paper›PMID 36593708›Full record

ArticleThe world journal of men's health2023

Patterns and Predictors of Optimal Surgical and Functional Outcomes after Holmium Laser Enucleation of the Prostate (HoLEP): Introducing the Concept of "Trifecta".

Antonio Andrea Grosso, Fabrizio Di Maida, Samuele Nardoni, Matteo Salvi, Sofia Giudici, Luca Lambertini, Anna Cadenar, Riccardo Tellini, Andrea Cocci, Andrea Mari and 2 more

2 registry-linked trialsOpen access · diamondAbstract read
In one paragraph

Article in The world journal of men's health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
4.8field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07429994 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

Predictors of Trifecta Achievement After Holmium Laser Enucleation of the Prostate

TypeinterventionalSponsorOndokuz Mayıs UniversityRan2026 to 2028Enrolled604ConditionsHoLEP, Trifecta Achievement, Urinary Incontinence Following Surgical Procedure, Clavien Dindo Surgical Complication ScaleArmsTransurethral Holmium Laser Enuclation of the Prostate
NCT07591688 not yet recruitingnot on this mapstarted 2026, after this paper: background citation

Predictive Value of Enucleation Ratio for Symptomatic Improvement After HoLEP: A Multicenter Prospective Cohort Study

TypeobservationalSponsorOndokuz Mayıs UniversityRan2026 to 2027Enrolled400ConditionsBenign Prostate Obstruction (BPO)ArmsHolmium laser enucleation of prostate (HoLEP)
3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

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  19. Predictors of early catheter replacement after HoLEP. Results from a high-volume laser center.International braz j urol : official journal of the Brazilian Society of Urology
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Antonio Andrea GrossoDepartment of Experimental and Clinical Medicine, University of Florence - Unit of Oncologic Minimally-Invasive Urology and Andrology, Careggi Hospital, Florence, Italy.ORCID https://orcid.org/0000-0001-5973-789X
Fabrizio Di MaidaDepartment of Experimental and Clinical Medicine, University of Florence - Unit of Oncologic Minimally-Invasive Urology and Andrology, Careggi Hospital, Florence, Italy.ORCID https://orcid.org/0000-0003-1885-4808
Samuele NardoniDepartment of Experimental and Clinical Medicine, University of Florence - Unit of Oncologic Minimally-Invasive Urology and Andrology, Careggi Hospital, Florence, Italy.
Matteo SalviDepartment of Experimental and Clinical Medicine, University of Florence - Unit of Oncologic Minimally-Invasive Urology and Andrology, Careggi Hospital, Florence, Italy.
Sofia GiudiciDepartment of Experimental and Clinical Medicine, University of Florence - Unit of Oncologic Minimally-Invasive Urology and Andrology, Careggi Hospital, Florence, Italy.
Luca LambertiniDepartment of Experimental and Clinical Medicine, University of Florence - Unit of Oncologic Minimally-Invasive Urology and Andrology, Careggi Hospital, Florence, Italy.ORCID https://orcid.org/0000-0002-5917-019X
Anna CadenarDepartment of Experimental and Clinical Medicine, University of Florence - Unit of Oncologic Minimally-Invasive Urology and Andrology, Careggi Hospital, Florence, Italy.ORCID https://orcid.org/0000-0001-7782-2318
Riccardo TelliniDepartment of Experimental and Clinical Medicine, University of Florence - Unit of Oncologic Minimally-Invasive Urology and Andrology, Careggi Hospital, Florence, Italy.ORCID https://orcid.org/0000-0003-2189-5352
Andrea CocciDepartment of Experimental and Clinical Medicine, University of Florence - Unit of Oncologic Minimally-Invasive Urology and Andrology, Careggi Hospital, Florence, Italy.ORCID https://orcid.org/0000-0003-0138-6294
Andrea MariDepartment of Experimental and Clinical Medicine, University of Florence - Unit of Oncologic Minimally-Invasive Urology and Andrology, Careggi Hospital, Florence, Italy.ORCID https://orcid.org/0000-0001-9070-5706
Andrea MinerviniDepartment of Experimental and Clinical Medicine, University of Florence - Unit of Oncologic Minimally-Invasive Urology and Andrology, Careggi Hospital, Florence, Italy.ORCID https://orcid.org/0000-0002-1994-1324
Agostino TuccioDepartment of Experimental and Clinical Medicine, University of Florence - Unit of Oncologic Minimally-Invasive Urology and Andrology, Careggi Hospital, Florence, Italy. agostinotuccio@yahoo.it.ORCID https://orcid.org/0000-0003-4747-867X
University of Florence · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe present study sought to provide reproducible and patient-oriented metrics to assess the rate of "successful" outcomes (Trifecta) following holmium laser enucleation of the prostate (HoLEP). Clinical and surgical predictors of failure to achieve Trifecta were investigated. MATERIALS AND

methodsWe queried our prospectively collected database of all patients treated with HoLEP between March 2017 and January 2021. Trifecta was defined as the contemporary presence of: (1) no postoperative complication within 3 months; (2) no urinary incontinence at 3-months follow-up; and (3) 3-month postoperative max flow-rate >15 mL/s. Cases were grouped according to Trifecta achievement. All surgical procedures were carried out by a single surgeon. Surgical experience was divided into two different eras according to the number of procedures conducted (surgical era). Multivariate logistic regression analysis was performed to assess predictors of Trifecta failure.

resultsOverall 305 patients were included. Of these, 192 patients (63.0%) achieved Trifecta. Preoperative patient-related features were comparable between the two groups, except for a higher post-void residual (PVR) in non-Trifecta patients (median 180

conclusionsIn our experience the rate of "successful" HoLEP, defined according to our newly introduced Trifecta metric, was 63.0%. We demonstrated that surgical strategy together with rising experience and baseline PVR are key elements to forecast the outcomes.

Indexed as

Benign prostatic hyperplasiaHolmiumLasersProstatectomy

Identifiers

PMID36593708
PMCPMC10307654
OpenAlexW4313437966

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.