Evidence map›Paper›PMID 36593079›Full record

ArticleBMJ case reports2023

Acute cortical blindness caused by neuropsychiatric systemic lupus erythematosus.

Alex Kaimin Wong, David Gordon Darby, Christopher Fong

Open access · greenAbstract readCase Reports
In one paragraph

Article in BMJ case reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Alex Kaimin WongDepartment of Internal Medicine, Box Hill Hospital, Melbourne, Victoria, Australia alex.wong2@easternhealth.org.au.ORCID http://orcid.org/0000-0003-1140-8741
David Gordon DarbyDepartment of Neurosciences, Central Clinical School, Monash University, Melbourne, Victoria, Australia.
Christopher FongDepartment of Rheumatology, Box Hill Hospital, Melbourne, Victoria, Australia.
Box Hill Hospital · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A man in his 30s, who presented with fevers and a diffuse purpuric rash, developed sudden-onset visual loss on day 2. He was unable to perceive light in either eye. Examination by a neurologist confirmed cortical blindness, and the MRI showed subtle juxtacortical infarcts and leptomeningeal enhancement in the occipital region. Further history taken in the patient's native language revealed a history of untreated systemic lupus erythematosus. A diagnosis of central nervous system lupus was made and he was treated promptly with pulse methylprednisolone and cyclophosphamide. His vision gradually improved to 80% on day 10 and eventually returned to baseline. He continued with high-dose prednisolone and monthly cyclophosphamide for 6 months and remained on hydroxychloroquine and mycophenolate mofetil with no relapses. This case shows the importance of approaching the uncommon but potentially dangerous issue of acute visual loss with a broad differential.

Indexed as

Blindness, CorticalLupus Erythematosus, SystemicLupus Vasculitis, Central Nervous SystemCyclophosphamideHumansMaleMethylprednisoloneVision DisordersCyclophosphamideMethylprednisoloneNeuroophthalmologySystemic lupus erythematosus

Identifiers

PMID36593079
PMCPMC9809294
OpenAlexW4313406814

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.