Evidence map›Paper›PMID 36592279›Full record

ArticleMaternal and child health journal2023

Adverse Maternal Experiences and Neonatal Abstinence Syndrome.

Khaleel S Hussaini, George Yocher

Open access · greenAbstract read
In one paragraph

Article in Maternal and child health journal, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Khaleel S HussainiDivision of Reproductive Health, Field Support Branch, Centers for Disease Control and Prevention, U.S. Department of Health and Human Services, Atlanta, GA, USA. lpk4@cdc.gov.ORCID http://orcid.org/0000-0002-7635-2622
George YocherDivision of Public Health, Delaware Department of Health and Social Services, 1351 W. North Street, Dover, DE, 19904, USA.
Centers for Disease Control and Prevention · USDelaware Division of Public Health · US

Funding

RFA-DP-21-001 Component A, Delaware PRAMS (Pregnancy Risk Assessment Monitoring System) ProjectU01DP006617 · DP · DELAWARE DIVISION OF PUBLIC HEALTH · PI YOCHER, GEORGE · 2020 to 2025
$912k
ACL HHS U01DP006239Intramural CDC HHS CC999999NCCDPHP CDC HHS U01 DP006239NCCDPHP CDC HHS U01 DP006617
6 · The paper itself

Abstract

objectivesTo propose a measure for adverse maternal experiences (AMEs) and examine if AMEs are independently associated with delivery of a neonatal abstinence syndrome (NAS) diagnosed infant.

methodsUsing the Pregnancy Risk Assessment Monitoring System (PRAMS) stressful life events questions, we constructed a composite measure of AMEs. We conducted a retrospective analysis of linked Birth Certificate Data, Hospital Discharge Data and PRAMS data for 2012-2018 using the composite measure. Our analytic sample included 6358 singleton deliveries. We calculated prevalence of NAS and AMEs and prevalence odds ratio (POR) for delivery of an NAS-diagnosed infant adjusting for maternal sociodemographic characteristics, pre-pregnancy depression, prescription medicine 12 months prior to pregnancy, and smoking during pregnancy.

resultsThe overall prevalence of NAS in Delaware during 2012-2018 was 2.2% (95% CI 1.8-2.6); 9.5% (95% CI 8.7-10.2) of women reported AMEs. After adjustment, women with AMEs had 1.1 times greater odds (aPOR 2.1; 95% CI 1.3-3.3) to deliver a NAS-diagnosed infant as compared with women without AMEs.

conclusionsAlthough the cross-sectional nature of the study limits drawing any causal inferences, there are co-occurring factors that support plausibility of an association between AMEs and delivering NAS-diagnosed infants. Addressing AMEs, mental health and substance use screening and treatment as part of preconception and prenatal care may mitigate risks.

Indexed as

Neonatal Abstinence SyndromeCross-Sectional StudiesFemaleHumansInfantInfant, NewbornPregnancyPrenatal CareRetrospective StudiesRisk AssessmentAdverse maternal experiencesDepressionItem response theoryLinked datasetsNeonatal abstinence syndromePRAMSStressful life events

Identifiers

PMID36592279
PMCPMC10949090
OpenAlexW4313424551

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.