ArticleAIDS and behavior2023
Mental Health, ART Adherence, and Viral Suppression Among Adolescents and Adults Living with HIV in South Africa: A Cohort Study.
Article in AIDS and behavior, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07514221 (Adaptation of Project Yes+ to Improve Mental Health and Reduce HIV-related Stigma Among Adolescent and Young Men Who Have Sex With Men Living With HIV in Vietnam), which is not on this map. Cited by 47 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Adaptation of Project Yes+ to Improve Mental Health and Reduce HIV-related Stigma Among Adolescent and Young Men Who Have Sex With Men Living With HIV in Vietnam
Who cites it
47 citing papers in PubMed, 53 citations in OpenAlex.
- The Effect of Depression on the Pathways Between an Economic Strengthening Intervention and ART Adherence in Youths with HIV: Findings from a Moderated Mediation Model of the Suubi + Adherence Cluster-Randomized Study.Prevention science : the official journal of the Society for Prevention Research · 2025Trial
- Disclosure Events and Psychosocial Well-Being Among Young South African Adults Living with HIV.International journal of behavioral medicine · 2025Trial
- Effect of the Friendship Bench Intervention on Antiretroviral Therapy Outcomes and Mental Health Symptoms in Rural Zimbabwe: A Cluster Randomized Trial.JAMA network open · 2023Trial
- A Scoping Review Assessing the Relationship Between Structural, Functional, and Perceived Social Support with Antiretroviral Therapy (ART) in the Last Decade.AIDS and behavior · 2026Article
- Major Depressive Episodes and Psychiatric Symptoms Among HIV Controllers Compared With Antiretroviral-Treated People Living With HIV.Open forum infectious diseases · 2026Article
- Cost-Effectiveness and Impact of Depression Treatment Implementation on HIV Outcomes in Western Kenya: A Mathematical Modelling Study.Journal of the International AIDS Society · 2026Article
- How has mental health impacted the HIV epidemic and how has the HIV epidemic impacted mental health in Western Kenya? A mathematical modelling study.BMJ global health · 2026Article
- A Moderated Mediation Model of HIV-Related Anticipated Stigma and Social Capital on the Relationship Between Diagnosis During the COVID-19 Pandemic and Potentially Problematic Substance Use Among Young South Africans.International journal of behavioral medicine · 2026Article
- Resilience and Its Determinants Among Adolescents and Young Adults with Perinatally Acquired HIV Enrolled in a Peer-Led Mentorship Program in India.AIDS and behavior · 2026Article
- Mental Wellness and Adherence Self-Efficacy Among Adolescents Living with HIV in the Cape Town Metropole: A Cross-Sectional Survey.Pediatric reports · 2026Article
- Association between documented mental health disorders and HIV treatment outcomes among adults receiving antiretroviral therapy in rural Zimbabwe.BioPsychoSocial medicine · 2026Article
- The relationship between self-reported adherence and virological outcomes among adolescents on antiretroviral therapy in Ghana.BMC public health · 2026Article
- Under the Influence: Alcohol, Substance Use and Treatment Adherence in Youth Living with HIV in the Global Adolescent and Young Adult Network of IeDEA (AYANI) Cohort.AIDS and behavior · 2026Article
- Determinants of Antiretroviral Treatment Adherence Among Young Mothers Living with HIV: The Role of Early Motherhood.AIDS and behavior · 2026Article
- Maladaptive Coping Strategies Mediate the Relationship Between Depression and Anxiety and Moderate-to-Heavy Alcohol Use in Young South Africans with HIV.AIDS and behavior · 2026Article
- Retreatment after loss of follow-up in adolescent and young adult patients living with HIV: a case-control study.Revista latino-americana de enfermagem · 2026Article
- Article
- HIV Care Through Their Eyes: Navigating HIV Services and ART Adherence Among Adolescents and Their Caregivers in Lusaka, Zambia.AIDS research and treatment · 2026Article
- ART adherence care strategies among adolescents living with HIV in Ghana's Ashanti Region: a qualitative study.Frontiers in public health · 2026Article
- Life-years lost associated with mental disorders in people with HIV: a cohort study in South Africa, Canada and the United States.Journal of the International AIDS Society · 2025Article
Corrections and comments
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Authors and funding
17 authors at 4 institutions in 5 countries.
Funding
Abstract
We followed adolescents and adults living with HIV aged older than 15 years who enrolled in a South African private-sector HIV programme to examine adherence and viral non-suppression (viral load > 400 copies/mL) of participants with (20,743, 38%) and without (33,635, 62%) mental health diagnoses. Mental health diagnoses were associated with unfavourable adherence patterns. The risk of viral non-suppression was higher among patients with organic mental disorders [adjusted risk ratio (aRR) 1.55, 95% confidence interval (CI) 1.22-1.96], substance use disorders (aRR 1.53, 95% CI 1.19-1.97), serious mental disorders (aRR 1.30, 95% CI 1.09-1.54), and depression (aRR 1.19, 95% CI 1.10-1.28) when compared with patients without mental health diagnoses. The risk of viral non-suppression was also higher among males, adolescents (15-19 years), and young adults (20-24 years). Our study highlights the need for psychosocial interventions to improve HIV treatment outcomes-particularly of adolescents and young adults-and supports strengthening mental health services in HIV treatment programmes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.