Evidence map›Paper›PMID 36591462›Full record

ArticleFrontiers in oncology2022

Oncologic impact of delay between diagnosis and radical nephroureterectomy.

Kuan-Hsien Wu, Chao-Hsiang Chang, Hsi-Chin Wu, Steven K Huang, Chien-Liang Liu, Cheng-Kuang Yang, Jian-Ri Li, Jen-Shu Tseng, Wun-Rong Lin, Chih-Chin Yu and 18 more

Abstract read
In one paragraph

Article in Frontiers in oncology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

28 authors.

Kuan-Hsien WuDepartment of Urology, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan.
Chao-Hsiang ChangDepartment of Urology, China Medical University and Hospital, Taichung, Taiwan.
Hsi-Chin WuDepartment of Urology, China Medical University and Hospital, Taichung, Taiwan.
Steven K HuangDivision of Urology, Department of Surgery, Chi Mei Medical Center, Tainan, Taiwan.
Chien-Liang LiuDivision of Urology, Department of Surgery, Chi Mei Medical Center, Tainan, Taiwan.
Cheng-Kuang YangDivision of Urology, Department of Surgery, Taichung Veterans General Hospital, Taichung, Taiwan.
Jian-Ri LiDivision of Urology, Department of Surgery, Taichung Veterans General Hospital, Taichung, Taiwan.
Jen-Shu TsengDepartment of Urology, MacKay Memorial Hospital, Taipei, Taiwan.
Wun-Rong LinDepartment of Urology, MacKay Memorial Hospital, Taipei, Taiwan.
Chih-Chin YuDivision of Urology, Department of surgery, Taipei Tzuchi Hospital, The Buddhist Tzu Chi Medical Foundation, New Taipei City, Taiwan.
Chi-Wen LoDivision of Urology, Department of surgery, Taipei Tzuchi Hospital, The Buddhist Tzu Chi Medical Foundation, New Taipei City, Taiwan.
Chao-Yuan HuangDepartment of Urology, National Taiwan University Hospital, College of Medicine, National Taiwan University, Taipei, Taiwan.
Chung-Hsin ChenDepartment of Urology, National Taiwan University Hospital, College of Medicine, National Taiwan University, Taipei, Taiwan.
Chung-You TsaiDivisions of Urology, Department of Surgery, Far Eastern Memorial Hospital, New Taipei City, Taiwan.
Pai-Yu ChengDivisions of Urology, Department of Surgery, Far Eastern Memorial Hospital, New Taipei City, Taiwan.
Yuan-Hong JiangDepartment of Urology, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation and Tzu Chi University, Hualien, Taiwan.
Yu-Khun LeeDepartment of Urology, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation and Tzu Chi University, Hualien, Taiwan.
Yung-Tai ChenDepartment of Urology, Taiwan Adventist Hospital, Taipei, Taiwan.
Ting-Chun YehDepartment of Urology, Taiwan Adventist Hospital, Taipei, Taiwan.
Jen-Tai LinDivision of Urology, Department of Surgery, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan.
Yao-Chou TsaiSchool of Medicine, Buddhist Tzu Chi University, Hualien, Taiwan.
Thomas Y HsuehDivision of Urology, Department of Surgery, Taipei City Hospital Renai Branch, Taipei, Taiwan.
Bing-Juin ChiangCollege of Medicine, Fu-Jen Catholic University, New Taipei City, Taiwan.
Yi-De ChiangDepartment of Urology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan.
Wei-Yu LinDivision of Urology, Department of Surgery, Chang Gung Memorial Hospital at Chiayi, Chiayi, Taiwan.
Yeong-Chin JouDepartment of Urology, Ditmanson Medical Foundation Chiayi Christian Hospital, Chiayi, Taiwan.
See-Tong PangDivision of Urology, Department of Surgery, Chang Gung Memorial Hospital, Linkou Branch, Taoyuan, Taiwan.
Hung-Lung KeDepartment of Urology, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: This study aimed to evaluate the oncological outcome of delayed surgical wait time from the diagnosis of upper tract urothelial carcinoma (UTUC) to radical nephroureterectomy (RNU). Methods: In this multicenter retrospective study, medical records were collected between 1988 and 2021 from 18 participating Taiwanese hospitals under the Taiwan UTUC Collaboration Group. Patients were dichotomized into the early (≤90 days) and late (>90 days) surgical wait-time groups. Overall survival, disease-free survival, and bladder recurrence-free survival were calculated using the Kaplan-Meier method and multivariate Cox regression analysis. Multivariate analysis was performed using stepwise linear regression. Results: Of the 1251 patients, 1181 (94.4%) were classifed into the early surgical wait-time group and 70 (5.6%) into the late surgical wait-time group. The median surgical wait time was 21 days, and the median follow-up was 59.5 months. Our study showed delay-time more than 90 days appeared to be associated with worse overall survival (hazard ratio [HR] 1.974, 95% confidence interval [CI] 1.166-3.343, Conclusions: For patients with UTUC undergoing RNU, the surgical wait time should be minimized to less than 90 days. Prolonged delay times may be associated with poor overall and disease-free survival.

Indexed as

nephroureterectomysurgical wait timesurvivalureteroscopyurinary tract urothelial carcinoma

Identifiers

PMID36591462
PMCPMC9795168

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.