Evidence map›Paper›PMID 36591450›Full record

ReviewFrontiers in oncology2022

Hypoxia-responsive nanomaterials for tumor imaging and therapy.

Yifei Xia, Shao Duan, Chaozhe Han, Chengwei Jing, Zunyu Xiao, Chao Li

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Frontiers in oncology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yifei XiaDepartment of Orthopedics, The Second Affiliated Hospital of Harbin Medical University, Harbin, China.
Shao DuanDepartment of Orthopedics, The Second Affiliated Hospital of Harbin Medical University, Harbin, China.
Chaozhe HanDepartment of Orthopedics, The Second Affiliated Hospital of Harbin Medical University, Harbin, China.
Chengwei JingDepartment of Orthopedics, The Second Affiliated Hospital of Harbin Medical University, Harbin, China.
Zunyu XiaoDepartment of Nuclear Medicine, The Fourth Hospital of Harbin Medical University, Harbin, China.
Chao LiDepartment of Orthopedics, The Second Affiliated Hospital of Harbin Medical University, Harbin, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hypoxia is an important component of tumor microenvironment and plays a pivotal role in cancer progression. With the distinctive physiochemical properties and biological effects, various nanoparticles targeting hypoxia had raised great interest in cancer imaging, drug delivery, and gene therapy during the last decade. In the current review, we provided a comprehensive view on the latest progress of novel stimuli-responsive nanomaterials targeting hypoxia-tumor microenvironment (TME), and their applications in cancer diagnosis and therapy. Future prospect and challenges of nanomaterials are also discussed.

Indexed as

cancer imagingdrug deliveryhypoxia tumor microenvironmentstimuli-responsive nanoparticletumor microenvironment targeted theranostics

Identifiers

PMID36591450
PMCPMC9798000

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.