Evidence map›Paper›PMID 36591350›Full record

ArticleKidney3602022

Urinary Citrate Is Associated with Kidney Outcomes in Early Polycystic Kidney Disease.

Daniel Ribeiro Rocha, Laixi Xue, Hiago Murilo Gomes Sousa, Ana Christina Carvalho Matos, Ewout J Hoorn, Mahdi Salih, Ita Pfeferman Heilberg

Open access · diamondAbstract read
In one paragraph

Article in Kidney360, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.2field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

  1. Trial
  2. Review
  3. Article
  4. A Urine pH-Ammonium Acid/Base Score and CKD Progression.Journal of the American Society of Nephrology : JASN · 2024
    Article
  5. Review
  6. Kidney phosphate wasting predicts poor outcome in polycystic kidney disease.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2024
    Observational
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Daniel Ribeiro RochaDivision of Nephrology, Universidade Federal de São Paulo (UNIFESP), São Paulo, Brazil.ORCID 0000-0002-7783-3778
Laixi XueDivision of Nephrology and Transplantation, Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands.ORCID 0000-0003-0837-6056
Hiago Murilo Gomes SousaDivision of Nephrology, Universidade Federal de São Paulo (UNIFESP), São Paulo, Brazil.
Ana Christina Carvalho MatosDivision of Nephrology, Universidade Federal de São Paulo (UNIFESP), São Paulo, Brazil.
Ewout J HoornDivision of Nephrology and Transplantation, Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands.
Mahdi SalihDivision of Nephrology and Transplantation, Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands.ORCID 0000-0002-4568-8967
Ita Pfeferman HeilbergDivision of Nephrology, Universidade Federal de São Paulo (UNIFESP), São Paulo, Brazil.ORCID 0000-0002-0885-5877
Universidade Federal de São Paulo · BRErasmus MC · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Low urinary citrate and crystal deposition accelerated cystogenesis in an experimental model of polycystic kidney disease (PKD).Hypocitraturia, frequently observed in patients with autosomal dominant PKD (ADPKD) could contribute to disease progression.Present findings suggest lower urinary citrate in early PKD was associated with faster eGFR decline and worse kidney survival.

Indexed as

CalcinosisPolycystic Kidney, Autosomal DominantCitric AcidDisease ProgressionHumansKidneyCitric AcidADPKDCKDcystic kidney diseaseeGFRpolycystic kidney diseaseurinary citrate

Identifiers

PMID36591350
PMCPMC9802559
OpenAlexW4306638538

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.