Evidence map›Paper›PMID 36591280›Full record

ArticleFrontiers in immunology2022

The impact on colostrum oxidative stress, cytokines, and immune cells composition after SARS-CoV-2 infection during pregnancy.

Nayara Gomes Graciliano, Micaely Cristinados Santos Tenório, Marilene Brandão Tenório Fragoso, Fabiana Andréa Moura, Rayane Martins Botelho, Eloiza Lopes Lira Tanabe, Karen Steponavicius Cruz Borbely, Alexandre Urban Borbely, Alane Cabral Menezes Oliveira, Marília Oliveira Fonseca Goulart

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Nayara Gomes GracilianoInstitute of Biological and Health Sciences, Federal University of Alagoas, Maceio, Alagoas, Brazil.
Micaely Cristinados Santos TenórioInstitute of Chemistry and Biotechnology, Federal University of Alagoas, Maceio, Alagoas, Brazil.
Marilene Brandão Tenório FragosoInstitute of Chemistry and Biotechnology, Federal University of Alagoas, Maceio, Alagoas, Brazil.
Fabiana Andréa MouraCollege of Nutrition, Federal University of Alagoas, Maceio, Alagoas, Brazil.
Rayane Martins BotelhoInstitute of Biological and Health Sciences, Federal University of Alagoas, Maceio, Alagoas, Brazil.
Eloiza Lopes Lira TanabeInstitute of Biological and Health Sciences, Federal University of Alagoas, Maceio, Alagoas, Brazil.
Karen Steponavicius Cruz BorbelyInstitute of Biological and Health Sciences, Federal University of Alagoas, Maceio, Alagoas, Brazil.
Alexandre Urban BorbelyInstitute of Biological and Health Sciences, Federal University of Alagoas, Maceio, Alagoas, Brazil.
Alane Cabral Menezes OliveiraInstitute of Biological and Health Sciences, Federal University of Alagoas, Maceio, Alagoas, Brazil.
Marília Oliveira Fonseca GoulartInstitute of Biological and Health Sciences, Federal University of Alagoas, Maceio, Alagoas, Brazil.
Universidade Federal de Alagoas · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Limited data are available regarding the differences between immunological, biochemical, and cellular contents of human colostrum following maternal infection during pregnancy with coronavirus 2 disease (COVID-19). Objective: To investigate whether maternal COVID-19 infection may affect immunological, biochemical, and cellular contents of human colostrum. Methods: Using a case-control study design, we collected colostrum from 14 lactating women with a previous diagnosis of COVID-19 during pregnancy and 12 without a clear diagnosis during September 2020 to May 2021. Colostrum samples were analysed for some enzymes and non-enzymatic oxidative stress markers (SOD, CAT, GPx, MDA, GSH, GSSG, H Results: Colostrum from the COVID-19 symptomatic group in pregnancy contained reduced levels of H Conclusion: The present results reinforce the protective role of colostrum even in the case of mild SARS-Cov-2 infection, in addition to demonstrating how adaptive the composition of colostrum is after infections. It also supports the recommendation to encourage lactating women to continue breastfeeding after COVID-19 illness.

Indexed as

COVID-19Pregnancy Complications, InfectiousCase-Control StudiesColostrumCytokinesFemaleGranulocyte-Macrophage Colony-Stimulating FactorHumansHydrogen PeroxideInterferon-gammaLactationPregnancySARS-CoV-2Spike Glycoprotein, CoronavirusCytokinesGranulocyte-Macrophage Colony-Stimulating FactorHydrogen PeroxideInterferon-gammaSpike Glycoprotein, Coronavirusspike protein, SARS-CoV-2antibodiesbreastfeedingCOVID-19human milkIgAimmunoglobulinspassive immunity

Identifiers

PMID36591280
PMCPMC9798093
OpenAlexW4311510433

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.