Evidence map›Paper›PMID 36591005›Full record

ReviewGenes & diseases2022

Advances of CRISPR-Cas13 system in COVID-19 diagnosis and treatment.

Qianqian Zhou, Yanhua Chen, Ruolei Wang, Fengjing Jia, Feng He, Fuwen Yuan

Abstract readReview
In one paragraph

Review in Genes & diseases, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Qianqian ZhouAcademy of Integrative Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.
Yanhua ChenAcademy of Integrative Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.
Ruolei WangAcademy of Integrative Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.
Fengjing JiaAcademy of Integrative Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.
Feng HeAcademy of Integrative Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.
Fuwen YuanAcademy of Integrative Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The ongoing global pandemic of coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has resulted in over 570 million infections and 6 million deaths worldwide. Early detection and quarantine are essential to arrest the spread of the highly contagious COVID-19. High-risk groups, such as older adults and individuals with comorbidities, can present severe symptoms, including pyrexia, pertussis, and acute respiratory distress syndrome, on SARS-CoV-2 infection that can prove fatal, demonstrating a clear need for high-throughput and sensitive platforms to detect and eliminate SARS-CoV-2. CRISPR-Cas13, an emerging CRISPR system targeting RNA with high specificity and efficiency, has recently drawn much attention for COVID-19 diagnosis and treatment. Here, we summarized the current research progress on CRISPR-Cas13 in COVID-19 diagnosis and treatment and highlight the challenges and future research directions of CRISPR-Cas13 for effectively counteracting COVID-19.

Indexed as

COVID-19CRISPR-Cas13DiagnosisSARS-CoV-2Treatment

Identifiers

PMID36591005
PMCPMC9793954

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.