Evidence map›Paper›PMID 36590965›Full record

SynthesisFrontiers in medicine2022

Coronavirus disease 2019 (COVID-19) excess mortality outcomes associated with pandemic effects study (COPES): A systematic review and meta-analysis.

David Lu, Sumeet Dhanoa, Harleen Cheema, Kimberley Lewis, Patrick Geeraert, Benjamin Merrick, Aaron Vander Leek, Meghan Sebastianski, Brittany Kula, Dipayan Chaudhuri and 9 more

Abstract readSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Frontiers in medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

David LuFaculty of Medicine and Dentistry, Alberta Health Services, University of Alberta, Edmonton, AB, Canada.
Sumeet DhanoaFaculty of Medicine and Dentistry, Alberta Health Services, University of Alberta, Edmonton, AB, Canada.
Harleen CheemaFaculty of Medicine and Dentistry, Alberta Health Services, University of Alberta, Edmonton, AB, Canada.
Kimberley LewisDepartment of Health Research Methods, Evidence and Impact, McMaster University, Hamilton, ON, Canada.
Patrick GeeraertFaculty of Medicine and Dentistry, Alberta Health Services, University of Alberta, Edmonton, AB, Canada.
Benjamin MerrickFaculty of Medicine and Dentistry, Alberta Health Services, University of Alberta, Edmonton, AB, Canada.
Aaron Vander LeekFaculty of Medicine and Dentistry, Alberta Health Services, University of Alberta, Edmonton, AB, Canada.
Meghan SebastianskiAlberta Strategy for Patient-Oriented Research Knowledge Translation Platform, University of Alberta, Edmonton, AB, Canada.
Brittany KulaDivision of Infectious Disease, Department of Medicine, Faculty of Medicine and Dentistry, Alberta Health Services, University of Alberta, Edmonton, AB, Canada.
Dipayan ChaudhuriDivision of Critical Care Medicine, Department of Medicine, McMaster University, Hamilton, ON, Canada.
John BasmajiDivision of Critical Care, Department of Medicine, Western University, London, ON, Canada.
Arnav AgrawalDepartment of Health Research Methods, Evidence and Impact, McMaster University, Hamilton, ON, Canada.
Dan NivenDepartment of Critical Care Medicine, Cumming School of Medicine, Alberta Health Services, University of Calgary, Calgary, AB, Canada.
Kirsten FiestDepartment of Critical Care Medicine, Cumming School of Medicine, Alberta Health Services, University of Calgary, Calgary, AB, Canada.
Henry T StelfoxDepartment of Critical Care Medicine, Cumming School of Medicine, Alberta Health Services, University of Calgary, Calgary, AB, Canada.
Danny J ZuegeDepartment of Critical Care Medicine, Cumming School of Medicine, Alberta Health Services, University of Calgary, Calgary, AB, Canada.
Oleksa G RewaDepartment of Critical Care Medicine, Faculty of Medicine and Dentistry, Alberta Health Services, University of Alberta, Edmonton, AB, Canada.
Sean M BagshawDepartment of Critical Care Medicine, Faculty of Medicine and Dentistry, Alberta Health Services, University of Alberta, Edmonton, AB, Canada.
Vincent I LauDepartment of Critical Care Medicine, Faculty of Medicine and Dentistry, Alberta Health Services, University of Alberta, Edmonton, AB, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and aim: With the Coronavirus Disease 2019 (COVID-19) pandemic continuing to impact healthcare systems around the world, healthcare providers are attempting to balance resources devoted to COVID-19 patients while minimizing excess mortality overall (both COVID-19 and non-COVID-19 patients). To this end, we conducted a systematic review (SR) to describe the effect of the COVID-19 pandemic on all-cause excess mortality (COVID-19 and non-COVID-19) during the pandemic timeframe compared to non-pandemic times. Methods: We searched EMBASE, Cochrane Database of SRs, MEDLINE, Cumulative Index to Nursing and Allied Health Literature (CINAHL) and Cochrane Controlled Trials Register (CENTRAL), from inception (1948) to December 31, 2020. We used a two-stage review process to screen/extract data. We assessed risk of bias using Newcastle-Ottawa Scale (NOS). We used Critical Appraisal and Grading of Recommendations Assessment, Development and Evaluation (GRADE) methodology. Results: Of 11,581 citations, 194 studies met eligibility. Of these studies, 31 had mortality comparisons ( Interpretation: The COVID-19 pandemic may have caused significant increases in all-cause excess mortality, greater than those accounted for by increases due to COVID-19 mortality alone, although the evidence is uncertain. Systematic review registration: [https://www.crd.york.ac.uk/prospero/#recordDetails], identifier [CRD42020201256].

Indexed as

COVID-19excess mortalitynon-COVID-19 mortalityoutcomespandemic (COVID-19)

Identifiers

PMID36590965
PMCPMC9800609

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.