ArticleFrontiers in psychiatry2022
Secondhand smoke is positively associated with pre-frailty and frailty in non-smoking older adults.
Article in Frontiers in psychiatry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 21 citations in OpenAlex.
- Frailty and Cardiovascular Risk.European cardiology · 2026Review
- Interaction Between Smoking and Olfactory Function on Frailty: A Population-Based Cross-Sectional Study.Health science reports · 2025Article
- Long-term smoking contributes to aging frailty and inflammatory response.Biomolecules & biomedicine · 2025Article
- Lifestyle, environment and other major determinants of frailty in older adults: a population-based study from the UK Biobank.Biogerontology · 2025Article
- Serum hydroxycotinine was associated with chronic kidney disease (CKD): a cross-sectional study based on NHANES.Renal failure · 2024Article
- High cotinine levels as an associated factor with frailty status in older adults: evidence from the NHANES study.BMC geriatrics · 2024Article
- Plant-based index linked to fall risk in older Chinese adults: cross-sectional evidence from a national cohort.Aging clinical and experimental research · 2024Article
- Article
- Effects of cigarette smoking and secondhand smoke exposure on physical frailty development among community-dwelling older adults in Japan: Evidence from a 10-year population-based cohort study.Geriatrics & gerontology international · 2024Article
- Association of remnant cholesterol with frailty: findings from observational and Mendelian randomization analyses.Lipids in health and disease · 2023Observational
- Household Polluting Fuel Use and Frailty among Older Adults in Rural China: The Moderating Role of Healthy Lifestyle Behaviors.Healthcare (Basel, Switzerland) · 2023Article
- Frailty is associated with worse cognitive functioning in older adults.Frontiers in psychiatry · 2023Article
- Concurrent serum lead levels and cognitive function in older adults.Frontiers in neuroscience · 2023Article
Corrections and comments
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Authors and funding
8 authors at 7 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: Either exposure to secondhand smoke (SHS) or frailty has been linked to adverse health outcomes in nonsmoking adults. However, their relationship is rarely studied. The purpose of this study is to examine the association between serum cotinine level and frailty status among non-smoking older adults. Method: The study population consisted of 2,703 older adults aged ≥60 from the National Health and Nutrition Examination Survey 2011-2014. Non-smokers were included based on (1) a serum cotinine level ≤ 10 ng/mL and 2) a response of "no" to the question, "Do you currently smoke?" Frailty status was measured based on the Fried Phenotype and had three groups- robust, pre-frailty, and frailty. Multinomial logistic regression models were constructed to examine the association between serum cotinine level quartile and frailty status, controlling for age, sex, race/ethnicity, education, depressive symptoms, alcohol use, and systolic blood pressure. Results: About half of the participants (median age 70.0 years, range 64-78) were female (53.6%), non-Hispanic White (48.3%), and completed some college and above (50.1%). Multinomial logistic regression with a reference group being those in the 1 Conclusions: Higher serum cotinine level is associated with increased risk of pre-frailty and frailty versus robust in non-smoking older adults. Prevention and reduction of SHS in older adults may help protect them from developing pre-frailty or frailty.
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