Evidence map›Paper›PMID 36590586›Full record

ArticleFrontiers in cellular and infection microbiology2022

A multicenter investigation of 2,773 cases of bloodstream infections based on China antimicrobial surveillance network (CHINET).

Fupin Hu, Lili Yuan, Yang Yang, Yuanhong Xu, Ying Huang, Yunjian Hu, Xiaoman Ai, Chao Zhuo, Danhong Su, Bin Shan and 14 more

Registry-linked trialAbstract readMulticenter Study
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06738771 (Antimicrobial Therapy for Infections Due to Pseudomonas Aeruginosa With Difficult-to-treat Resistance), which is not on this map. Cited by 42 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06738771 recruitingnot on this mapstarted 2025, after this paper: background citation

Antimicrobial Therapy for Infections Due to Pseudomonas Aeruginosa With Difficult-to-treat Resistance: a Real-world, Prospective, Multicenter Cohort Study

TypeobservationalSponsorCentre Hospitalier Régional d'OrléansRan2025 to 2027Enrolled600ConditionsPseudomonas Infections, Pseudomonas Aeruginosa, Prognosis, Drug Resistance, Multiple, Bacterial
3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors.

Fupin HuInstitute of Antibiotics, Huashan Hospital, Fudan University, Shanghai, China.
Lili YuanDepartment of Hospital Infection Management, Huashan Hospital, Fudan University, Shanghai, China.
Yang YangInstitute of Antibiotics, Huashan Hospital, Fudan University, Shanghai, China.
Yuanhong XuClinical Microbiology Laboratory, The First Affiliated Hospital of Anhui Medical University, Hefei, China.
Ying HuangClinical Microbiology Laboratory, The First Affiliated Hospital of Anhui Medical University, Hefei, China.
Yunjian HuClinical Microbiology Laboratory, Beijing Hospital, Beijing, China.
Xiaoman AiClinical Microbiology Laboratory, Beijing Hospital, Beijing, China.
Chao ZhuoDepartment of Infectious Disease, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
Danhong SuClinical Microbiology Laboratory, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
Bin ShanClinical Microbiology Laboratory, The First Affiliated Hospital of Kunming Medical University, Kunming, China.
Yan DuClinical Microbiology Laboratory, The First Affiliated Hospital of Kunming Medical University, Kunming, China.
Yunsong YuDepartment of Infectious Disease, Sir Run Run Shaw Hospital, Affiliated to Zhejiang University School of Medicine, Hangzhou, China.
Jie LinClinical Microbiology Laboratory, Sir Run Run Shaw Hospital, Affiliated to Zhejiang University School of Medicine, Hangzhou, China.
Ziyong SunClinical Microbiology Laboratory, Tongji Hospital Affiliated to Tongji Medical College of Huazhong University of Science and Technology, Wuhan, China.
Zhongju ChenClinical Microbiology Laboratory, Tongji Hospital Affiliated to Tongji Medical College of Huazhong University of Science and Technology, Wuhan, China.
Yingchun XuClinical Microbiology Laboratory, Peking Union Medical College Hospital, Beijing, China.
Xiaojiang ZhangClinical Microbiology Laboratory, Peking Union Medical College Hospital, Beijing, China.
Chuanqing WangClinical Microbiology Laboratory, Children's Hospital of Fudan University, Shanghai, China.
Leiyan HeClinical Microbiology Laboratory, Children's Hospital of Fudan University, Shanghai, China.
Yuxing NiClinical Microbiology Laboratory, Ruijin Hospital Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai, China.
Yibo ZhangDepartment of Hospital Infection Management, Ruijin Hospital Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai, China.
Dongfang LinInstitute of Antibiotics, Huashan Hospital, Fudan University, Shanghai, China.
Demei ZhuInstitute of Antibiotics, Huashan Hospital, Fudan University, Shanghai, China.
Yingyuan ZhangInstitute of Antibiotics, Huashan Hospital, Fudan University, Shanghai, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Bloodstream infections (BSIs), especially hospital-acquired BSIs, are a major cause of morbidity and mortality. However, the details about the pathogens and antimicrobial resistance profile of BSIs across China are still lacking. Methods: An investigation was conducted in 10 large teaching hospitals from seven geographic regions across China in 2016 based on China Antimicrobial Surveillance Network (CHINET) to profile the clinical and etiological features of BSIs. Results: A total of 2,773 cases of BSIs were identified, a majority (97.3%) of which were monomicrobial. Overall, 38.4% (1,065/2,773) were community-acquired BSIs (CABSIs), and 61.6% (1,708/2,773) were hospital-acquired BSIs (HABSIs). Of the 2,861 pathogenic BSI isolates, 67.5% were Gram-negative bacteria, 29.6% were Gram-positive bacteria, and 2.9% were fungi. The top BSI pathogens were Conclusions: The findings about BSIs in teaching hospitals across China add more scientific evidence to inform the appropriate management of the disease.

Indexed as

Anti-Infective AgentsBacteremiaCross InfectionMethicillin-Resistant Staphylococcus aureusSepsisAmpicillinAnti-Bacterial AgentsCefepimeCeftazidimeChinaDrug Resistance, BacterialEscherichia coliHumansMicrobial Sensitivity TestsStaphylococcusStaphylococcus aureusAmpicillinAnti-Bacterial AgentsAnti-Infective AgentsCefepimeCeftazidimeSulbactamsultamicillinantimicrobial susceptibility testingbloodstream infectioncommunity-acquiredhospital-acquiredmulticenter investigation

Identifiers

PMID36590586
PMCPMC9798236

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.