Evidence map›Paper›PMID 36590540›Full record

ArticleHeliyon2022

Peptide Utility (PU) search server: A new tool for peptide sequence search from multiple databases.

Tanishq Chamoli, Alisha Khera, Akanksha Sharma, Anshul Gupta, Sonam Garg, Kanishk Mamgain, Aayushi Bansal, Shriya Verma, Ankit Gupta, Hema K Alajangi and 2 more

Open access · goldAbstract read
In one paragraph

Article in Heliyon, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Tanishq ChamoliDepartment of Computer Science and Engineering, Chandigarh College of Engineering and Technology, Chandigarh, India.
Alisha KheraDepartment of Biophysics, Panjab University, Chandigarh 160014, India.
Akanksha SharmaDepartment of Biophysics, Panjab University, Chandigarh 160014, India.
Anshul GuptaDepartment of Computer Science and Engineering, Chandigarh College of Engineering and Technology, Chandigarh, India.
Sonam GargDepartment of Computer Science and Engineering, Chandigarh College of Engineering and Technology, Chandigarh, India.
Kanishk MamgainDepartment of Computer Science and Engineering, Chandigarh College of Engineering and Technology, Chandigarh, India.
Aayushi BansalDepartment of Computer Science and Engineering, Chandigarh College of Engineering and Technology, Chandigarh, India.
Shriya VermaDepartment of Computer Science and Engineering, Chandigarh College of Engineering and Technology, Chandigarh, India.
Ankit GuptaDepartment of Computer Science and Engineering, Chandigarh College of Engineering and Technology, Chandigarh, India.
Hema K AlajangiDepartment of Biophysics, Panjab University, Chandigarh 160014, India.
Gurpal SinghUniversity Institute of Pharmaceutical Sciences, Panjab University, Chandigarh 160014, India.
Ravi P BarnwalDepartment of Computer Science and Engineering, Chandigarh College of Engineering and Technology, Chandigarh, India.
Punjab Engineering College · INPanjab University · INNational Centre for Cell Science · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Proteins are essential building blocks in humans that have garnered huge attention from researchers worldwide due to their numerous therapeutic applications. To date, different computational tools have been developed to extract pre-existing information on these biological molecules, but most of these tools suffer from limitations such as non-user friendly interface, redundancy of data, etc. To overcome these limitations, a user-friendly interface, the Peptide Utility (PU) webserver (https://chain-searching.herokuapp.com/) has been developed for searching and analyzing homologous and identical protein/peptide sequences that can be searched from approximately 0.4 million sequences (structural and sequence information) in both online and offline modes. The PU web server can also be used to study different types of interactions in PDBSum, identifying the most dominating interface residues, the most prevalent interactions, and the interaction preferences of different residues. The webserver would also pave way for the design of novel therapeutic peptides and folds by identifying conserved residues in the three-dimensional structure space of proteins.

Indexed as

Homologous pairsIdentical pairsPDBPeptide sequenceProteins

Identifiers

PMID36590540
PMCPMC9800339
OpenAlexW4313453841

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.