Evidence map›Paper›PMID 36590526›Full record

ArticleHeliyon2022

Improved interface packing and design opportunities revealed by CryoEM analysis of a designed protein nanocage.

Stephen McCarthy, Shane Gonen

Open access · goldAbstract read
In one paragraph

Article in Heliyon, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.3field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Stephen McCarthyDepartment of Molecular Biology and Biochemistry, University of California, Irvine, CA 92617, USA.
Shane GonenDepartment of Molecular Biology and Biochemistry, University of California, Irvine, CA 92617, USA.
University of California, Irvine · US

Funding

Breaking barriers in CryoEM through computational protein designR35GM142797 · NIGMS · UNIVERSITY OF CALIFORNIA-IRVINE · PI GONEN, SHANE · 2021 to 2025
$1.9M
NIGMS NIH HHS R35 GM142797
6 · The paper itself

Abstract

Symmetric protein assemblies play important roles in nature which makes them an attractive target for engineering.

Indexed as

Computational protein designCryoEMIcosahedralNanomaterialStructureSymmetry

Identifiers

PMID36590526
PMCPMC9801105
OpenAlexW4311472535

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.