Evidence map›Paper›PMID 36590466›Full record

ArticleiScience2022

Learning to control a BMI-driven wheelchair for people with severe tetraplegia.

Luca Tonin, Serafeim Perdikis, Taylan Deniz Kuzu, Jorge Pardo, Bastien Orset, Kyuhwa Lee, Mirko Aach, Thomas Armin Schildhauer, Ramón Martínez-Olivera, José Del R Millán

Open access · goldAbstract read
In one paragraph

Article in iScience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
4.9field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 45 citations in OpenAlex.

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  8. Non-Invasive Brain-Computer Interfaces: State of the Art and Trends.IEEE reviews in biomedical engineering · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 5 countries.

Luca ToninDepartment of Information Engineering, University of Padova, Padova, Italy.
Serafeim PerdikisBrain-Computer Interfaces and Neural Engineering Laboratory, School of Computer Science and Electronic Engineering, University of Essex, Colchester, UK.
Taylan Deniz KuzuKlinik für Neurochirurgie und Wirbelsäulenchirurgie, Universitätsklinikum Bergmannsheil Bochum, Ruhr-Universität Bochum, Bochum, Germany.
Jorge PardoKlinik für Neurochirurgie und Wirbelsäulenchirurgie, Universitätsklinikum Bergmannsheil Bochum, Ruhr-Universität Bochum, Bochum, Germany.
Bastien OrsetÉcole Polytechnique Fédérale de Lausanne, Geneva, Switzerland.
Kyuhwa LeeWyss Center for Bio and Neuroengineering, Geneva, Switzerland.
Mirko AachChirurgische Universitätsklinik und Poliklinik, Universitätsklinikum Bergmannsheil Bochum, Ruhr-Universität Bochum, Bochum, Germany.
Thomas Armin SchildhauerChirurgische Universitätsklinik und Poliklinik, Universitätsklinikum Bergmannsheil Bochum, Ruhr-Universität Bochum, Bochum, Germany.
Ramón Martínez-OliveraKlinik für Neurochirurgie und Wirbelsäulenchirurgie, Universitätsklinikum Bergmannsheil Bochum, Ruhr-Universität Bochum, Bochum, Germany.
José Del R MillánDepartment of Electrical and Computer Engineering, The University of Texas at Austin, Austin, TX, USA.
BG University Hospital Bergmannsheil Bochum · DEÉcole Polytechnique Fédérale de Lausanne · CHThe University of Texas at Austin · USUniversity of Essex · GBUniversity of Padua · ITWyss Center for Bio and Neuroengineering · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mind-controlled wheelchairs are an intriguing assistive mobility solution applicable in complete paralysis. Despite progress in brain-machine interface (BMI) technology, its translation remains elusive. The primary objective of this study is to probe the hypothesis that BMI skill acquisition by end-users is fundamental to control a non-invasive brain-actuated intelligent wheelchair in real-world settings. We demonstrate that three tetraplegic spinal-cord injury users could be trained to operate a non-invasive, self-paced thought-controlled wheelchair and execute complex navigation tasks. However, only the two users exhibiting increasing decoding performance and feature discriminancy, significant neuroplasticity changes and improved BMI command latency, achieved high navigation performance. In addition, we show that dexterous, continuous control of robots is possible through low-degree of freedom, discrete and uncertain control channels like a motor imagery BMI, by blending human and artificial intelligence through shared-control methodologies. We posit that subject learning and shared-control are the key components paving the way for translational non-invasive BMI.

Indexed as

Machine learningRoboticsTechniques in neuroscience

Identifiers

PMID36590466
PMCPMC9801246
OpenAlexW4309484358

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.