Evidence map›Paper›PMID 36590172›Full record

ArticleiScience2023

Stepwise remodeling and subcompartment formation in individual vesicles by three ESCRT-III proteins.

Yunuen Avalos-Padilla, Vasil N Georgiev, Eleanor Ewins, Tom Robinson, Esther Orozco, Reinhard Lipowsky, Rumiana Dimova

Open access · goldAbstract read
In one paragraph

Article in iScience, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. Devising a divisome for synthetic cells.Nature reviews. Chemistry · 2026
    Review
  2. Review
  3. Membrane-Associated Biomolecules for Synthetic Cell Signalling.Chembiochem : a European journal of chemical biology · 2026
    Review
  4. Photoswitchable Endocytosis of Biomolecular Condensates in Giant Vesicles.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024
    Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 3 countries.

Yunuen Avalos-PadillaMax Planck Institute of Colloids and Interfaces, Science Park Golm, 14476 Potsdam, Germany.
Vasil N GeorgievMax Planck Institute of Colloids and Interfaces, Science Park Golm, 14476 Potsdam, Germany.
Eleanor EwinsMax Planck Institute of Colloids and Interfaces, Science Park Golm, 14476 Potsdam, Germany.
Tom RobinsonMax Planck Institute of Colloids and Interfaces, Science Park Golm, 14476 Potsdam, Germany.
Esther OrozcoDepartamento de Infectómica y Patogénesis Molecular, CINVESTAV IPN, 07360 Ciudad de México, México.
Reinhard LipowskyMax Planck Institute of Colloids and Interfaces, Science Park Golm, 14476 Potsdam, Germany.
Rumiana DimovaMax Planck Institute of Colloids and Interfaces, Science Park Golm, 14476 Potsdam, Germany.
Max Planck Institute of Colloids and Interfaces · DECentro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The endosomal sorting complex required for transport (ESCRT) is a multi-protein machinery involved in several membrane remodeling processes. Different approaches have been used to resolve how ESCRT proteins scission membranes. However, the underlying mechanisms generating membrane deformations are still a matter of debate. Here, giant unilamellar vesicles, microfluidic technology, and micropipette aspiration are combined to continuously follow the ESCRT-III-mediated membrane remodeling on the single-vesicle level for the first time. With this approach, we identify different mechanisms by which a minimal set of three ESCRT-III proteins from

Indexed as

BiophysicsBiotechnologyCell biologyMembranes

Identifiers

PMID36590172
PMCPMC9800321
OpenAlexW4310905475

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.