Evidence map›Paper›PMID 36589905›Full record

ArticleSensors and actuators. B, Chemical2023

A novel linear displacement isothermal amplification with strand displacement probes (LDIA-SD) in a pocket-size device for point-of-care testing of infectious diseases.

Hongchao Gou, Qijie Lin, Haiyan Shen, Kaiyuan Jia, Yucen Liang, Junhao Peng, Chunhong Zhang, Xiaoyun Qu, Yanbin Li, Jianhan Lin and 2 more

Open access · greenAbstract read
In one paragraph

Article in Sensors and actuators. B, Chemical, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.7field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 6 institutions in 2 countries.

Hongchao GouInstitute of Animal Health, Guangdong Academy of Agricultural Sciences, Guangzhou, China.
Qijie LinNational and Regional Joint Engineering Laboratory for Medicament of Zoonoses Prevention and Control, Guangzhou 510642, China.
Haiyan ShenInstitute of Animal Health, Guangdong Academy of Agricultural Sciences, Guangzhou, China.
Kaiyuan JiaNational and Regional Joint Engineering Laboratory for Medicament of Zoonoses Prevention and Control, Guangzhou 510642, China.
Yucen LiangNational and Regional Joint Engineering Laboratory for Medicament of Zoonoses Prevention and Control, Guangzhou 510642, China.
Junhao PengNational and Regional Joint Engineering Laboratory for Medicament of Zoonoses Prevention and Control, Guangzhou 510642, China.
Chunhong ZhangInstitute of Animal Health, Guangdong Academy of Agricultural Sciences, Guangzhou, China.
Xiaoyun QuNational and Regional Joint Engineering Laboratory for Medicament of Zoonoses Prevention and Control, Guangzhou 510642, China.
Yanbin LiDepartment of Biological and Agricultural Engineering, University of Arkansas, Fayetteville, AR 72701, USA.
Jianhan LinKey Laboratory of Agricultural Information Acquisition Technology, Ministry of Agriculture and Rural Affairs, China Agricultural University, Beijing 100083, China.
Jianmin ZhangNational and Regional Joint Engineering Laboratory for Medicament of Zoonoses Prevention and Control, Guangzhou 510642, China.
Ming LiaoInstitute of Animal Health, Guangdong Academy of Agricultural Sciences, Guangzhou, China.
Key Laboratory of Guangdong Province · CNGuangdong Provincial Center for Disease Control and Prevention · CNSouth China Agricultural University · CNChina Agricultural University · CNGuangdong Academy of Agricultural Sciences · CNUniversity of Arkansas at Fayetteville · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nucleic acid amplification is crucial for disease diagnosis, especially lethal infectious diseases such as COVID-19. Compared with PCR, isothermal amplification methods are advantageous for point-of-care testing (POCT). However, complicated primer design limits their application in detecting some short targets or sequences with abnormal GC content. Herein, we developed a novel linear displacement isothermal amplification (LDIA) method using two pairs of conventional primers and

Indexed as

Infectious diseasesIsothermal amplificationLinear displacement isothermal amplification (LDIA)Nucleic Acid AmplificationPoint-of-care testing (POCT)

Identifiers

PMID36589905
PMCPMC9789534
OpenAlexW4313453516

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.