Evidence map›Paper›PMID 36589904›Full record

ArticleSensors and actuators. B, Chemical2023

A colorimetric lateral flow immunoassay based on oriented antibody immobilization for sensitive detection of SARS-CoV-2.

Ae Sol Lee, Su Min Kim, Kyeong Rok Kim, Chulmin Park, Dong-Gun Lee, Hye Ryoung Heo, Hyung Joon Cha, Chang Sup Kim

Open access · greenAbstract read
In one paragraph

Article in Sensors and actuators. B, Chemical, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
3.9field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 48 citations in OpenAlex.

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  15. Diverse applications and development of aptamer detection technology.Analytical sciences : the international journal of the Japan Society for Analytical Chemistry · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Ae Sol LeeGraduate School of Biochemistry, Yeungnam University, Gyeongsan 38541, Republic of Korea.
Su Min KimGraduate School of Biochemistry, Yeungnam University, Gyeongsan 38541, Republic of Korea.
Kyeong Rok KimGraduate School of Biochemistry, Yeungnam University, Gyeongsan 38541, Republic of Korea.
Chulmin ParkVaccine Bio Research Institute, College of Medicine, Seoul St. Mary's Hospital, The Catholic University of Korea, Seoul 06591, Republic of Korea.
Dong-Gun LeeVaccine Bio Research Institute, College of Medicine, Seoul St. Mary's Hospital, The Catholic University of Korea, Seoul 06591, Republic of Korea.
Hye Ryoung HeoSenotherapy-based Metabolic Disease Control Research Center, Yeungnam University, Gyeongsan 38541, Republic of Korea.
Hyung Joon ChaDepartment of Chemical Engineering, Pohang University of Science and Technology, Pohang 37673, Republic of Korea.
Chang Sup KimGraduate School of Biochemistry, Yeungnam University, Gyeongsan 38541, Republic of Korea.
Yeungnam University · KRCatholic University of Korea · KRPohang University of Science and Technology · KRSeoul St. Mary's Hospital · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes coronavirus disease 2019 (COVID-19). The high human-to-human transmission and rapid evolution of SARS-CoV-2 have resulted in a worldwide pandemic. To contain SARS-CoV-2, it is essential to efficiently control the transmission of the virus through the early diagnosis of infected individuals, including asymptomatic people. Therefore, a rapid and accurate assay is vital for the early diagnosis of SARS-CoV-2 in suspected individuals. In this study, we developed a colorimetric lateral flow immunoassay (LFIA) in which a CBP31-BC linker was used to immobilize antibodies on a cellulose membrane in an oriented manner. The developed LFIA enabled sensitive detection of cultured SARS-CoV-2 in 15 min with a detection limit of 5 × 10

Indexed as

AntibodyCOVID-19Lateral flow immunoassayOrientationSARS-CoV-2Sensitive

Identifiers

PMID36589904
PMCPMC9791791
OpenAlexW4313442557

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.