Evidence map›Paper›PMID 36589860›Full record

ArticlePCN reports : psychiatry and clinical neurosciences2022

Aging and Neural Vulnerabilities in Overeating: A Conceptual Overview and Model to Guide Treatment.

W Jack Rejeski, Paul J Laurienti, Mohsen Bahrami, Jason Fanning, Sean L Simpson, Jonathan H Burdette

Open access · goldAbstract read
In one paragraph

Article in PCN reports : psychiatry and clinical neurosciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. Trial
  2. Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

W Jack RejeskiDepartment of Health and Exercise Science, Wake Forest University, Winston-Salem, NC, USA.ORCID 0000-0003-2281-4649
Paul J LaurientiLaboratory for Complex Brain Networks, Wake Forest University School of Medicine, Winston-Salem, NC, USA.
Mohsen BahramiLaboratory for Complex Brain Networks, Wake Forest University School of Medicine, Winston-Salem, NC, USA.
Jason FanningDepartment of Health and Exercise Science, Wake Forest University, Winston-Salem, NC, USA.
Sean L SimpsonLaboratory for Complex Brain Networks, Wake Forest University School of Medicine, Winston-Salem, NC, USA.
Jonathan H BurdetteLaboratory for Complex Brain Networks, Wake Forest University School of Medicine, Winston-Salem, NC, USA.
Wake Forest University · US

Funding

Wake Forest Claude D. Pepper OAIC - RenewalP30AG021332 · NIA · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI Jamie Nicole Justice · 2002 to 2026
$36.4M
The Mobile Devices for Meal Timing (MD4MT) Study: A supplement to HALLO-P using multiple wearable devise to improve accuracy in meal timing for older adults2U01AG073240 · NIA · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI KRITCHEVSKY, STEPHEN B., MILLER, MICHAEL E. · 2021 to 2024
$4.4M
Intervening on sedentary behavior to prevent weight regain in older adultsR01AG051624 · NIA · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI NICKLAS, BARBARA J, REJESKI, WALTER JOHN · 2016 to 2020
$3.8M
NIA NIH HHS P30 AG021332NIA NIH HHS R01 AG051624NIA NIH HHS U01 AG073240
6 · The paper itself

Abstract

Given the vulnerability of older adults to chronic disease and physical disability, coupled with the threat that obesity poses to healthy aging, there is an urgent need to understand the causes of positive energy balance and the struggle that many older adults face with intentional weight loss. This paper focuses on neural vulnerabilities related to overeating in older adults, and moderating variables that can have either favorable or unfavorable effect these vulnerabilities. Research from our laboratory on older adults with obesity suggests that they are prone to similar neural vulnerabilities for overeating that have been observed in younger and middle-aged populations. In addition, following brief postabsorptive states, functional brain networks both in the resting state and in response to active imagery of desired food are associated with 6-month weight loss. Data reviewed suggest that the sensorimotor network is a central hub in the process of valuation and underscores the central role played by habits in overeating. Finally, we demonstrate how research on the neural vulnerabilities for overeating offers a useful framework for guiding clinical decision-making in weight management.

Indexed as

AgingBrainbrain imagingneural networksobesityolder adultsweight loss

Identifiers

PMID36589860
PMCPMC9797202
OpenAlexW4292259712

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.