Evidence map›Paper›PMID 36589738›Full record

ArticleFrontiers in cell and developmental biology2022

A new model for fatty acid hydroxylase-associated neurodegeneration reveals mitochondrial and autophagy abnormalities.

Frida Mandik, Yuliia Kanana, Jost Rody, Sophie Misera, Bernd Wilken, Björn-Hergen Laabs von Holt, Christine Klein, Melissa Vos

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in cell and developmental biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 12 citations in OpenAlex.

  1. Clinical, Radiological, and Genetic Profile of Patients withTremor and other hyperkinetic movements (New York, N.Y.) · 2026
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  4. Insects · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Frida MandikInstitute of Neurogenetics, University of Luebeck, UKSH, Luebeck, Germany.
Yuliia KananaInstitute of Neurogenetics, University of Luebeck, UKSH, Luebeck, Germany.
Jost RodyInstitute of Neurogenetics, University of Luebeck, UKSH, Luebeck, Germany.
Sophie MiseraInstitute of Neurogenetics, University of Luebeck, UKSH, Luebeck, Germany.
Bernd WilkenDepartment of Neuropediatrics, Klinikum Kassel, Kassel, Germany.
Björn-Hergen Laabs von HoltInstitut für Medizinische Biometrie und Statistik, University of Luebeck, Luebeck, Germany.
Christine KleinInstitute of Neurogenetics, University of Luebeck, UKSH, Luebeck, Germany.
Melissa VosInstitute of Neurogenetics, University of Luebeck, UKSH, Luebeck, Germany.
University of Lübeck · DEKlinikum Kassel · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fatty acid hydroxylase-associated neurodegeneration (FAHN) is a rare disease that exhibits brain modifications and motor dysfunctions in early childhood. The condition is caused by a homozygous or compound heterozygous mutation in

Indexed as

autophagyDrosophila melanogasterFA2Hfatty acid hydroxylase-associated neurodegenerationmitochondria

Identifiers

PMID36589738
PMCPMC9794614
OpenAlexW4311329986

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.