ArticleAdvanced photonics research2022
In Vivo Assessment and Monitoring of Burn Wounds Using a Handheld Terahertz Hyperspectral Scanner.
Article in Advanced photonics research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed.
- Terahertz spectral imaging for early assessment of frostbite injuries using the double Debye model and supervised machine learning.Biomedical optics express · 2026Article
- All-fibre-coupled terahertz single-pixel imaging for biomedical applications.Nature communications · 2026Article
- Review
- Multi-layered model for simulating theBiomedical optics express · 2025Article
- Robotically Controlled Terahertz Probe for In Vivo Skin Evaluation: Imaging with the PicoBot.Journal of infrared, millimeter and terahertz waves · 2025Article
- Limitations of effective medium models for tissue phantoms in the THz frequency range.Scientific reports · 2024Article
- Terahertz polarimetric imaging of biological tissue: Monte Carlo modeling of signal contrast mechanisms due to Mie scattering.Biomedical optics express · 2024Article
- [Construction of the burn rehabilitation system].Zhonghua shao shang yu chuang mian xiu fu za zhi · 2023Article
- Terahertz polarimetric imaging of biological tissues: Monte Carlo modeling of signal contrast mechanisms due to Mie scattering.Research square · 2023Article
- [Strengthening the development and application of precision burn medicine].Zhonghua shao shang yu chuang mian xiu fu za zhi · 2023Article
- Polarimetric imaging of back-scattered terahertz speckle fields using a portable scanner.Optics express · 2023Article
- Triage ofBiomedical optics express · 2023Article
- Assessing Corneal Endothelial Damage Using Terahertz Time-Domain Spectroscopy and Support Vector Machines.Sensors (Basel, Switzerland) · 2022Article
- Accurate and early prediction of the wound healing outcome of burn injuries using the wavelet Shannon entropy of terahertz time-domain waveforms.Journal of biomedical optics · 2022Article
- Terahertz PHASR Scanner with 2 kHz, 100 picosecond Time-Domain Trace Acquisition Rate and an Extended Field-of-View Based on a Heliostat Design.IEEE transactions on terahertz science and technology · 2022Article
- Multiresolution spectrally-encoded terahertz reflection imaging through a highly diffusive cloak.Optics express · 2022Article
- Deep neural network classification of in vivo burn injuries with different etiologies using terahertz time-domain spectral imaging.Biomedical optics express · 2022Article
- Supervised machine learning for automatic classification of in vivo scald and contact burn injuries using the terahertz Portable Handheld Spectral Reflection (PHASR) Scanner.Scientific reports · 2022Article
- Translation-Invariant Zero-Phase Wavelet Methods for Feature Extraction in Terahertz Time-Domain Spectroscopy.Sensors (Basel, Switzerland) · 2022Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
The accuracy of clinical assessment techniques in diagnosing partial-thickness burn injuries has remained as low as 50-76%. Depending on the burn depth and environmental factors in the wound, such as reactive oxygen species, inflammation, and autophagy, partial-thickness burns can heal spontaneously or require surgical intervention. Herein, it is demonstrated that terahertz time-domain spectral imaging (THz-TDSI) is a promising tool for in vivo quantitative assessment and monitoring of partial-thickness burn injuries in large animals. We used a novel handheld THz-TDSI scanner to characterize burn injuries in a porcine scald model with histopathological controls. Statistical analysis (n= 40) indicates that the THz-TDSI modality can accurately differentiate between partial-thickness and full-thickness burn injuries (1-way ANOVA, p< 0.05). THz-TDSI has the potential to improve burn care outcomes by helping surgeons in making objective decisions for early excision of the wound.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.