Evidence map›Paper›PMID 36589681›Full record

ArticleOxidative medicine and cellular longevity2022

Inositol Alleviates Pulmonary Fibrosis by Promoting Autophagy via Inhibiting the HIF-1

Yufeng Liang, Yingyi Xu, Bingtai Lu, Yuanming Huang, Shuman Xu, Junjie Xie, Ming Liu, Di Che, Liuheyi Ma, Jianping Tao and 8 more

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Oxidative medicine and cellular longevity, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 4 institutions in 1 country.

Yufeng LiangPediatric Intensive Care Unit, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, Guangdong, China.
Yingyi XuDepartment of Anaesthesiology, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, Guangdong, China.
Bingtai LuGuangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China.
Yuanming HuangMedical Management Department of Guangdong Province Hospital for Women and Children Healthcare, Guangzhou, Guangdong, China.
Shuman XuMedical Management Department of Guangdong Province Hospital for Women and Children Healthcare, Guangzhou, Guangdong, China.
Junjie XieMaternal and Child Health Hospital of Sanshui District, Foshan, Guangdong, China.
Ming LiuGuangzhou Institute of Pediatrics, Guangzhou. Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, Guangdong, China.
Di CheGuangzhou Institute of Pediatrics, Guangzhou. Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, Guangdong, China.
Liuheyi MaGuangzhou Institute of Pediatrics, Guangzhou. Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, Guangdong, China.
Jianping TaoPediatric Intensive Care Unit, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, Guangdong, China.
Jie HongPediatric Intensive Care Unit, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, Guangdong, China.
Jianhui ZhangPediatric Intensive Care Unit, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, Guangdong, China.
Xun SituPediatric Intensive Care Unit, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, Guangdong, China.
XinXu OuDepartment of Anaesthesiology, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, Guangdong, China.
Lihe ChenLibrary, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, Guangdong, China.
Yang LiDepartment of Pediatrics, Linzhi People's Hospital, Linzhi, Tibet, China.
Lihong ZhangDepartment of Pediatrics, Linzhi People's Hospital, Linzhi, Tibet, China.ORCID https://orcid.org/0000-0003-3996-0458
Zhiyuan WuPediatric Intensive Care Unit, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, Guangdong, China.ORCID https://orcid.org/0000-0001-5346-7956
Guangzhou Women and Children Medical Center · CNTibet University · CNGuangdong Province Women and Children Hospital · CNFoshan Maternity and Child Health Care Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The effective remission of acute respiratory distress syndrome- (ARDS-) caused pulmonary fibrosis determines the recovery of lung function. Inositol can relieve lung injuries induced by ARDS. However, the mechanism of myo-inositol in the development of ARDS is unclear, which limits its use in the clinic. We explored the role and mechanism of myo-inositol in the development of ARDS by using an

Indexed as

Pulmonary FibrosisRespiratory Distress SyndromeAnimalsAutophagyCadherinsEpithelial-Mesenchymal TransitionInositolLipopolysaccharidesMiceSignal TransductionCadherinsInositolLipopolysaccharides

Identifiers

PMID36589681
PMCPMC9803570
OpenAlexW4312103070

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.