Evidence map›Paper›PMID 36589666›Full record

ArticleOncology letters2023

Prognostic risk factors for pT4 colon cancer: A retrospective cohort study.

Tsutomu Kumamoto, Shigeki Yamaguchi, Ryosuke Nakagawa, Yoji Nagashima, Fumi Maeda, Kimitaka Tani, Hiroka Kondo, Kurodo Koshino, Yuka Kaneko, Yoshiko Bamba and 3 more

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Oncology letters, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 1 institution in 1 country.

Tsutomu KumamotoDepartment of Surgery, Division of Colorectal Surgery, Tokyo Women's Medical University, Tokyo 162-8666, Japan.
Shigeki YamaguchiDepartment of Surgery, Division of Colorectal Surgery, Tokyo Women's Medical University, Tokyo 162-8666, Japan.
Ryosuke NakagawaDepartment of Surgery, Division of Colorectal Surgery, Tokyo Women's Medical University, Tokyo 162-8666, Japan.
Yoji NagashimaDepartment of Surgical Pathology, Tokyo Women's Medical University, Tokyo 162-8666, Japan.
Fumi MaedaDepartment of Surgery, Division of Colorectal Surgery, Tokyo Women's Medical University, Tokyo 162-8666, Japan.
Kimitaka TaniDepartment of Surgery, Division of Colorectal Surgery, Tokyo Women's Medical University, Tokyo 162-8666, Japan.
Hiroka KondoDepartment of Surgery, Division of Colorectal Surgery, Tokyo Women's Medical University, Tokyo 162-8666, Japan.
Kurodo KoshinoDepartment of Surgery, Division of Colorectal Surgery, Tokyo Women's Medical University, Tokyo 162-8666, Japan.
Yuka KanekoDepartment of Surgery, Division of Colorectal Surgery, Tokyo Women's Medical University, Tokyo 162-8666, Japan.
Yoshiko BambaDepartment of Surgery, Division of Colorectal Surgery, Tokyo Women's Medical University, Tokyo 162-8666, Japan.
Shimpei OgawaDepartment of Surgery, Division of Colorectal Surgery, Tokyo Women's Medical University, Tokyo 162-8666, Japan.
Yuji InoueDepartment of Surgery, Division of Colorectal Surgery, Tokyo Women's Medical University, Tokyo 162-8666, Japan.
Michio ItabashiDepartment of Surgery, Division of Colorectal Surgery, Tokyo Women's Medical University, Tokyo 162-8666, Japan.
Tokyo Women's Medical University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The present study aimed to clarify the prognostic risk factors for pathological T4 (pT4) colon cancer and provide a basis for improved treatment in affected patients. The current retrospective cohort study included 83 consecutively enrolled patients who underwent curative surgery for primary pT4 colon cancer between January 2014 and December 2021 at Tokyo Medical Women's University (Tokyo, Japan). Oncological outcomes, including recurrence pattern, were compared between patients with pT4a and pT4b colon cancer. Independent risk factors associated with overall survival (OS) and relapse-free survival (RFS) were analyzed using a multivariate Cox regression model. The 3-year OS rates were 85.1 and 95.0% in the pT4a and pT4b groups (P=0.089) and 3-year RFS rates were 64.1 and 60.5% (P=0.589), respectively. Moreover, the 3-year peritoneal recurrence-free survival was 71.0 and 90.2% (P=0.085) in these groups, respectively. Independent risk factors for OS were histology (mucinous or poorly differentiated adenocarcinoma), tumor location (right-sided) and pN status (positive). The risk factors for RFS were histology and pN status. Patients with pT4b colon cancer and R

Indexed as

colon cancerlocally advanced cancermultivisceral resectionpathological T4prognostic factorR0 resection

Identifiers

PMID36589666
PMCPMC9773323
OpenAlexW4310173779

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.