Evidence map›Paper›PMID 36589588›Full record

ArticleBiomedical optics express2022

High-throughput and high-accuracy diagnosis of multiple myeloma with multi-object detection.

Liye Mei, Hui Shen, Yalan Yu, Yueyun Weng, Xiaoxiao Li, Kashif Rafiq Zahid, Jin Huang, Du Wang, Sheng Liu, Fuling Zhou and 1 more

Open access · goldAbstract read
In one paragraph

Article in Biomedical optics express, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.1field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 2 countries.

Liye MeiThe Institute of Technological Sciences, Wuhan University, Wuhan, 430072, China.
Hui ShenThe Department of Hematology, Zhongnan Hospital of Wuhan University, 430062, China.
Yalan YuThe Department of Hematology, Zhongnan Hospital of Wuhan University, 430062, China.
Yueyun WengThe Institute of Technological Sciences, Wuhan University, Wuhan, 430072, China.ORCID https://orcid.org/0000-0001-8910-8904
Xiaoxiao LiThe Institute of Technological Sciences, Wuhan University, Wuhan, 430072, China.
Kashif Rafiq ZahidDepartment of Radiation Oncology, Indiana University Melvin and Bren Simon Comprehensive Cancer Center, Indiana University School of Medicine, Indianapolis, IN 46202, USA.
Jin HuangThe Institute of Technological Sciences, Wuhan University, Wuhan, 430072, China.
Du WangThe Institute of Technological Sciences, Wuhan University, Wuhan, 430072, China.ORCID https://orcid.org/0000-0002-0098-7613
Sheng LiuThe Institute of Technological Sciences, Wuhan University, Wuhan, 430072, China.
Fuling ZhouThe Department of Hematology, Zhongnan Hospital of Wuhan University, 430062, China.
Cheng LeiThe Institute of Technological Sciences, Wuhan University, Wuhan, 430072, China.ORCID https://orcid.org/0000-0001-8439-4235
Wuhan University · CNUniversity School · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Multiple myeloma (MM) is a type of blood cancer where plasma cells abnormally multiply and crowd out regular blood cells in the bones. Automated analysis of bone marrow smear examination is considered promising to improve the performance and reduce the labor cost in MM diagnosis. To address the drawbacks in established methods, which mainly aim at identifying monoclonal plasma cells (monoclonal PCs) via binary classification, in this work, considering that monoclonal PCs is not the only basis in MM diagnosis, for the first we construct a multi-object detection model for MM diagnosis. The experimental results show that our model can handle the images at a throughput of 80 slides/s and identify six lineages of bone marrow cells with an average accuracy of 90.8%. This work makes a step further toward full-automatic and high-efficiency MM diagnosis.

Identifiers

PMID36589588
PMCPMC9774865
OpenAlexW4309322235

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.