Evidence map›Paper›PMID 36589552›Full record

ArticleBiomedical optics express2022

Decoherence of photon entanglement by transmission through brain tissue with Alzheimer's disease.

E J Galvez, B Sharma, F K Williams, C-J You, B Khajavi, J Castrillon, L Shi, S Mamani, L A Sordillo, L Zhang and 1 more

Abstract read
In one paragraph

Article in Biomedical optics express, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

E J GalvezDepartment of Physics and Astronomy, Colgate University, 13 Oak Drive, Hamilton, New York 13346, USA.ORCID https://orcid.org/0000-0003-0918-2245
B SharmaDepartment of Physics and Astronomy, Colgate University, 13 Oak Drive, Hamilton, New York 13346, USA.
F K WilliamsDepartment of Physics and Astronomy, Colgate University, 13 Oak Drive, Hamilton, New York 13346, USA.
C-J YouDepartment of Physics and Astronomy, Colgate University, 13 Oak Drive, Hamilton, New York 13346, USA.
B KhajaviDepartment of Physics and Astronomy, Colgate University, 13 Oak Drive, Hamilton, New York 13346, USA.ORCID https://orcid.org/0000-0001-6492-8914
J CastrillonDepartment of Physics and Astronomy, Colgate University, 13 Oak Drive, Hamilton, New York 13346, USA.
L ShiDepartment of Bioengineering, University of California-San Diego, 9500 Gilman Drive, La Jolla, California 92093, USA.ORCID https://orcid.org/0000-0003-1373-3206
S MamaniInstitute for Ultrafast Spectroscopy and Lasers-Physics Department, The City College of New York, 160 Convent Avenue, New York, NY 10031, USA.ORCID https://orcid.org/0000-0002-1041-910X
L A SordilloInstitute for Ultrafast Spectroscopy and Lasers-Physics Department, The City College of New York, 160 Convent Avenue, New York, NY 10031, USA.ORCID https://orcid.org/0000-0002-8195-242X
L ZhangInstitute for Ultrafast Spectroscopy and Lasers-Physics Department, The City College of New York, 160 Convent Avenue, New York, NY 10031, USA.
R R AlfanoInstitute for Ultrafast Spectroscopy and Lasers-Physics Department, The City College of New York, 160 Convent Avenue, New York, NY 10031, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The generation, manipulation and quantification of non-classical light, such as quantum-entangled photon pairs, differs significantly from methods with classical light. Thus, quantum measures could be harnessed to give new information about the interaction of light with matter. In this study we investigate if quantum entanglement can be used to diagnose disease. In particular, we test whether brain tissue from subjects suffering from Alzheimer's disease can be distinguished from healthy tissue. We find that this is indeed the case. Polarization-entangled photons traveling through brain tissue lose their entanglement via a decohering scattering interaction that gradually renders the light in a maximally mixed state. We found that in thin tissue samples (between 120 and 600 micrometers) photons decohere to a distinguishable lesser degree in samples with Alzheimer's disease than in healthy-control ones. Thus, it seems feasible that quantum measures of entangled photons could be used as a means to identify brain samples with the neurodegenerative disease.

Identifiers

PMID36589552
PMCPMC9774879

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.