Evidence map›Paper›PMID 36589504›Full record

ArticleRadiology case reports2023

Imaging characterization of an adult H3 K27M-altered diffuse midline glioma of the medulla oblongata with a confounding steroid response.

Claudia Godi, Paolo Garofalo, Marcella Callea, Paolo Vezzulli, Maurizio Barbera, Carlo Mandelli, Elena Mazza, Bianca Pollo, Maria Rosa Terreni, Antonella Castellano and 2 more

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Radiology case reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 1 country.

Claudia GodiNeuroradiology Unit and CERMAC, IRCCS San Raffaele Scientific Institute, Via Olgettina 60, 20132, Milan, Italy.
Paolo GarofaloPoliclinico Universitario di Monserrato, Cagliari University, Cagliari, Italy.
Marcella CalleaDepartment of Pathology, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Paolo VezzulliNeuroradiology Unit and CERMAC, IRCCS San Raffaele Scientific Institute, Via Olgettina 60, 20132, Milan, Italy.
Maurizio BarberaNeuroradiology Unit and CERMAC, IRCCS San Raffaele Scientific Institute, Via Olgettina 60, 20132, Milan, Italy.
Carlo MandelliDepartment of Neurosurgery, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Elena MazzaDepartment of Medical Oncology, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Bianca PolloNeuropathology, Fondazione IRCCS Istituto Neurologico C. Besta, Milan, Italy.
Maria Rosa TerreniDepartment of Pathology, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Antonella CastellanoNeuroradiology Unit and CERMAC, IRCCS San Raffaele Scientific Institute, Via Olgettina 60, 20132, Milan, Italy.
Nicoletta AnzaloneNeuroradiology Unit and CERMAC, IRCCS San Raffaele Scientific Institute, Via Olgettina 60, 20132, Milan, Italy.
Andrea FaliniNeuroradiology Unit and CERMAC, IRCCS San Raffaele Scientific Institute, Via Olgettina 60, 20132, Milan, Italy.
Istituti di Ricovero e Cura a Carattere Scientifico · ITVita-Salute San Raffaele University · ITIstituto di Ricovero e Cura a Carattere Scientifico San RaffaeleFondazione IRCCS Istituto Neurologico Carlo Besta · ITUniversity of Cagliari · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report an uncommon, infratentorial localization of adult H3 K27M-altered diffuse midline glioma arising in a particularly rare site (medulla oblongata). In addition to this unusual presentation, the lesion exhibited a substantial contrast enhancement and size decrease after dexamethasone, generating diagnostic dilemmas. Histology, molecular details, advanced Magnetic Resonance imaging features and differential diagnoses are here described and discussed, as well as common misconceptions about steroid-sensitive mass lesions, and practical difficulties for clinicians involved in the process of making diagnosis.

Indexed as

Diffuse midline gliomaHigh-grade gliomaMagnetic resonance imagingMedullaSteroid response

Identifiers

PMID36589504
PMCPMC9794887
OpenAlexW4311843018

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.