Evidence map›Paper›PMID 36589427›Full record

ArticleFrontiers in physiology2022

Omega-3 polyunsaturated fatty acid-induced vasodilation in mouse aorta and mesenteric arteries is not mediated by ATP-sensitive potassium channels.

Cristiana Bercea, Roshan Limbu, Kamila Behnam, Keat-Eng Ng, Qadeer Aziz, Andrew Tinker, Francesco Tamagnini, Graeme S Cottrell, Alister J McNeish

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in physiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Cristiana BerceaMcNeish Laboratory, School of Chemistry, Food and Pharmacy, Department of Pharmacology, University of Reading, London, United Kingdom.
Roshan LimbuMcNeish Laboratory, School of Chemistry, Food and Pharmacy, Department of Pharmacology, University of Reading, London, United Kingdom.
Kamila BehnamMcNeish Laboratory, School of Chemistry, Food and Pharmacy, Department of Pharmacology, University of Reading, London, United Kingdom.
Keat-Eng NgTinker Laboratory, William Harvey Research Institute, Clinical Pharmacology and Precision Medicine, Queen Mary University, London, United Kingdom.
Qadeer AzizTinker Laboratory, William Harvey Research Institute, Clinical Pharmacology and Precision Medicine, Queen Mary University, London, United Kingdom.
Andrew TinkerTinker Laboratory, William Harvey Research Institute, Clinical Pharmacology and Precision Medicine, Queen Mary University, London, United Kingdom.
Francesco TamagniniMcNeish Laboratory, School of Chemistry, Food and Pharmacy, Department of Pharmacology, University of Reading, London, United Kingdom.
Graeme S CottrellMcNeish Laboratory, School of Chemistry, Food and Pharmacy, Department of Pharmacology, University of Reading, London, United Kingdom.
Alister J McNeishMcNeish Laboratory, School of Chemistry, Food and Pharmacy, Department of Pharmacology, University of Reading, London, United Kingdom.
University of Reading · GBWilliam Harvey Research Institute · GB

Funding

British Heart Foundation FS/14/33/30799British Heart Foundation FS/PHD/20/29049British Heart Foundation PG/19/57/34568British Heart Foundation RG/15/15/31742
6 · The paper itself

Abstract

There is strong evidence that the omega-3 polyunsaturated fatty acids (n-3 PUFAs) docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA) have cardioprotective effects. n-3 PUFAs cause vasodilation in hypertensive patients, in part controlled by increased membrane conductance to potassium. As K

Indexed as

DHAEPAKATPomega-3 fatty-acidsPNU-37883Apotassium channels

Identifiers

PMID36589427
PMCPMC9797959
OpenAlexW4311510905

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.