Evidence map›Paper›PMID 36589139›Full record

ArticleAdvanced synthesis & catalysis2022

Synthesis of Saturated N-Heterocycles via a Catalytic Hydrogenation Cascade.

Tobias Wagener, Marco Pierau, Arne Heusler, Frank Glorius

Abstract read
In one paragraph

Article in Advanced synthesis & catalysis, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Journal of the American Chemical Society · 2023
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Tobias WagenerWestfälische Wilhelms-Universität Münster Organisch-Chemisches Institut Corrensstraße 40 48149 Münster Germany.
Marco PierauWestfälische Wilhelms-Universität Münster Organisch-Chemisches Institut Corrensstraße 40 48149 Münster Germany.
Arne HeuslerWestfälische Wilhelms-Universität Münster Organisch-Chemisches Institut Corrensstraße 40 48149 Münster Germany.
Frank GloriusWestfälische Wilhelms-Universität Münster Organisch-Chemisches Institut Corrensstraße 40 48149 Münster Germany.ORCID 0000-0002-0648-956X

Funding

European Research Council 788558
6 · The paper itself

Abstract

Saturated N-heterocycles are prominent motifs found in various natural products and pharmaceuticals. Despite the increasing interest in this class of compounds, the synthesis of saturated bicyclic azacycles requires tedious multi-step syntheses. Herein, we present a one-pot protocol for the synthesis of octahydroindoles, decahydroquinolines, and octahydroindolizines through a cascade reaction.

Indexed as

Domino reactionsHeterogeneous catalysisHydrogenationNitrogen heterocyclesRhodium

Identifiers

PMID36589139
PMCPMC9796080

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.