Evidence map›Paper›PMID 36589004›Full record

ArticleHeart rhythm O22022

Left bundle branch pacing-optimized implantable cardioverter-defibrillator (LOT-ICD) for cardiac resynchronization therapy: A pilot study.

Shunmuga Sundaram Ponnusamy, Vadivelu Ramalingam, Vithiya Ganesan, Thabish Syed, Mahesh Kumar, Selvaganesh Mariappan, Senthil Murugan, William Basil, Pugazhendhi Vijayaraman

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Heart rhythm O2, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06745778 (Evolution of Intracardiac Electrograms Recorded by Left Bundle Branch Pacing Lead in Patients With ICD or CRT-D), which is not on this map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
3.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06745778 recruitingnot on this mapstarted 2025, after this paper: background citation

Evolution of Intracardiac Electrograms Recorded by Left Bundle Branch Pacing Lead in Patients With ICD or CRT-D

TypeobservationalSponsorMedtronic Cardiac Rhythm and Heart FailureRan2025 to 2026Enrolled50ConditionsVentricular Tachycardia (VT), Ventricular Fibrillation
3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Cost-effective CRT using dual-chamber generators in patients without atrial pacing need.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2026
    Article
  3. [ICD electrode implantation for left bundle branch area pacing].Herzschrittmachertherapie & Elektrophysiologie · 2025
    Review
  4. Letter to the Editor: Building on Promising Evidence for Dual-Chamber ICDs in LBBAP.Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc · 2025
    Article
  5. Left bundle branch pacing in patients with structural heart disease: personalizing cardiac resynchronization therapy.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2025
    Review
  6. Article
  7. Article
  8. Is conduction system pacing a panacea for pacemaker therapy?Expert review of medical devices · 2024
    Review
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Shunmuga Sundaram PonnusamyDepartment of Cardiology, Velammal Medical College, Madurai, India.
Vadivelu RamalingamDepartment of Cardiology, Velammal Medical College, Madurai, India.
Vithiya GanesanDepartment of Microbiology, Velammal Medical College, Madurai, India.
Thabish SyedDepartment of Cardiology, Velammal Medical College, Madurai, India.
Mahesh KumarDepartment of Cardiology, Velammal Medical College, Madurai, India.
Selvaganesh MariappanDepartment of Cardiology, Velammal Medical College, Madurai, India.
Senthil MuruganDepartment of Cardiology, Velammal Medical College, Madurai, India.
William BasilMedtronic India Private Limited, Mumbai, India.
Pugazhendhi VijayaramanGeisinger Heart Institute, Geisinger Commonwealth School of Medicine, Wilkes Barre, Pennsylvania.
Velammal Medical College Hospital and Research Institute · INGeisinger Commonwealth School of Medicine · USMedtronic (India) · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Left bundle branch pacing (LBBP) involves direct capture of left bundle fibers by placing the lead deep inside the interventricular septum. Several studies have shown the feasibility and efficacy of LBBP as an alternative modality for cardiac resynchronization therapy (CRT). This paper describes approach for providing cost effective CRT with defibrillator (CRT-D) by LBBP and dual chamber implantable cardioverter defibrillator (ICD) which we label as LBBP optimized ICD (LOT-ICD). LBBP was performed using C315 sheath and 3830 Selectsecure lead in all patients by premature ventricular complex guided approach. In patients with complete correction of conduction system disease, IS-1 connector plug of the IS-1/DF-1 lead was capped and 3830 lead connected to the dual chamber ICD pulse-generator at RV-P/S port. LOT-ICD provided stable R-wave sensing for arrhythmia monitoring and resulted in cost-effective resynchronization therapy at reduced fluoroscopy duration and radiation dose.

Indexed as

Cardiac resynchronization therapyHeart failureImplantable cardioverter-defibrillatorLeft bundle branch pacingLeft bundle branch pacing–optimized implantable cardioverter-defibrillator

Identifiers

PMID36589004
PMCPMC9795261
OpenAlexW4311903361

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.