Evidence map›Paper›PMID 36588991›Full record

ArticleHeart rhythm O22022

Sex differences on outcomes of catheter ablation of ventricular tachycardia in patients with structural heart disease: A real-world systematic review and meta-analysis.

Narut Prasitlumkum, Leenhapong Navaravong, Aditya Desai, Pol Chewcharat, Haresh Gandhi, Prinka Perswani, Saraschandra Vallabhajosyula, Wisit Cheungpasitporn, Nazem Akoum, Krit Jongnarangsin and 1 more

Erratum issuedOpen access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Heart rhythm O2, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 8 institutions in 2 countries.

Narut PrasitlumkumDivision of Cardiology, University of California, Riverside, Riverside, California.
Leenhapong NavaravongDivision of Cardiovascular Medicine, University of Utah School of Medicine, Salt Lake City, Utah.
Aditya DesaiDepartment of Internal Medicine, University of California, Riverside, Riverside, California.
Pol ChewcharatDepartment of Epidemiology, Harvard University, Boston, Massachusetts.
Haresh GandhiDepartment of Internal Medicine, University of California, Riverside, Riverside, California.
Prinka PerswaniDepartment of Internal Medicine, University of California, Riverside, Riverside, California.
Saraschandra VallabhajosyulaDepartment of Internal Medicine, Mayo Clinic, Rochester, Minnesota.
Wisit CheungpasitpornSection of Cardiovascular Medicine, Department of Medicine, Wake Forest University School of Medicine, Winston-Salem, North Carolina.
Nazem AkoumDivision of Cardiovascular Medicine, University of Washington School of Medicine, Seattle, Washington.
Krit JongnarangsinDivision of Cardiac Electrophysiology, University of Michigan, Ann Arbor, Michigan.
Ronpichai ChokesuwattanaskulDivision of Cardiovascular Medicine, Center of Excellence in Arrhythmia Research, Department of Medicine, Faculty of Medicine, Chulalongkorn University and King Chulalongkorn Memorial Hospital, Thai Red Cross Society, Bangkok, Thailand.
University of California, Riverside · USHarvard University · USKing Chulalongkorn Memorial Hospital · THMayo Clinic · USUniversity of Michigan · USUniversity of Utah · USUniversity of Washington · USWake Forest University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Sex differences have diversely affected cardiac diseases. Little is known whether these differences impact outcomes of catheter ablation of ventricular tachycardia (VT). Objectives: To assess the impact of sex differences on outcomes of catheter ablation of VT. Methods: Databases were searched from inception through December 2021. Effect estimates from individual studies were extracted and combined using the random-effects, generic inverse variance method of DerSimonian and Laird. The outcomes of interest included VT recurrence rates, all-cause mortality, and composite outcomes of mortality, left ventricular assistant device use, and heart transplantation following VT ablation. Results: Our analysis included 22 observational studies. There were 10,206 patients, of which 12.8% were women. We found no statistical difference between sexes for VT recurrence rate (pooled hazard ratio [HR] 1.04, Conclusion: Our contemporary analysis suggests that sex may have no impact on clinical outcomes of catheter ablation of VT in patients with structural heart disease, though women are the underrepresented. However, recent VT ablation registries have involved more women in their studies. Future studies with a higher proportion of women are encouraged to verify the current perception.

Indexed as

AblationGenderMeta-analysisMortalityRecurrence ratesSexSystematic reviewVentricular tachycardia

Identifiers

PMID36588991
PMCPMC9795314
OpenAlexW4312084230

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.