ArticleFrontiers in neurology2022
Prefrontal brain function in patients with chronic insomnia disorder: A pilot functional near-infrared spectroscopy study.
Article in Frontiers in neurology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.
- Effects of acupuncture on the brain in primary insomnia: a coordinate-based meta-analysis of fMRI studies.Frontiers in neurology · 2023Pooled it
- Trial
- Effects of Night Shifts on Sleep, Cognitive Performance, and Anxiety in Emergency Nurses: An Observational Within-Subject Study.Journal of nursing management · 2026Observational
- The impact of 24-h activity patterns on executive function in older adults with chronic diseases: analysis of the isotonic substitution effect.Frontiers in public health · 2026Article
- Cortical activation and functional connectivity during verbal fluency task in patients with chronic insomnia: a multi-channel fNIRS study.Scientific reports · 2025Article
- Applications of Functional Near-Infrared Spectroscopy (fNIRS) in Monitoring Treatment Response in Psychiatry: A Scoping Review.Journal of clinical medicine · 2025Review
- Prefrontal Cortex Oxygenation During Exercise in Older Adults with Motoric Cognitive Risk Syndrome.Advanced biology · 2025Article
- Reduced frontotemporal connectivity during a verbal fluency task in patients with anxiety, sleep, and major depressive disorders.Frontiers in neurology · 2025Article
- The impact of sleep disorders on brain network connectivity in postpartum women: a functional near-infrared spectroscopy-based study.Frontiers in neurology · 2024Article
- The brain in chronic insomnia and anxiety disorder: a combined structural and functional fMRI study.Frontiers in psychiatry · 2024Article
- Prefrontal cortex functional connectivity changes during verbal fluency test in adults with short-term insomnia disorder: a functional near-infrared spectroscopy study.Frontiers in neuroscience · 2023Article
- Acceptance and commitment therapy for nurses' sleep, rumination, psychological flexibility, and it's neural mechanism: A randomized controlled fNIRS study.International journal of clinical and health psychology : IJCHPArticle
- Ultrasound-guided stellate ganglion acupuncture for chronic insomnia disorder using fNIRS: study protocol for a randomized controlled trial.Frontiers in neurologyArticle
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purpose: Insomnia is one of the most common diseases in elderly patients, which seriously affect the quality of life and psychological state of patients. The purpose of this study was to investigate the changes in the functional network pattern of the prefrontal cortex in patients with chronic insomnia disorder (CID) after taking drugs, using non-invasive and low-cost functional neuroimaging with multi-channel near-infrared spectroscopy (fNIRS). Methods: All subjects were assessed using the Pittsburgh Sleep Quality Index (PSQI), Hamilton Depression Scale (HAMD), Hamilton Anxiety Scale (HAMA), and fNIRS. The fNIRS assessment consists of two parts: the verbal fluency test (VFT) task state and the resting state, which assessed the differences in prefrontal activation and functional connectivity, respectively. Results: A total of 30 patients with chronic insomnia disorder (CID) and 15 healthy peers completed the study. During the VFT task, a significantly lower PFC activation was observed in patients with insomnia compared to the control group ( Conclusion: A weak prefrontal cortex response was detected in patients with CID when performing the VFT task, which could be enhanced by taking hypnotics. The weakened right prefrontal lobe network may play a role in the development of CID. fNIRS may serve as a potential tool to assess sleep status and guide drug therapy.
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