ArticleThe International journal of angiology : official publication of the International College of Angiology, Inc2022
Calcific Aortic Valve Stenosis with Aging and Current Development in its Pathophysiology.
Article in The International journal of angiology : official publication of the International College of Angiology, Inc, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 8 citations in OpenAlex.
- Impact of cardiac amyloidosis on survival in aortic stenosis patients undergoing TAVR: a systematic review and reconstructed time-to-event meta-analysis.The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology · 2026Article
- Gamma-Oryzanol Attenuates Aortic Valve Interstitial Cell Calcification via Suppression of BMP2-SMAD and MAPK Signaling Pathways.Biomolecules · 2026Article
- Analysis of risk factors and construction of nomogram model for cardiac valve calcification of patients undergoing hemodialysis.Frontiers in cardiovascular medicine · 2026Article
- Mineral composition and ratios in aortic valves, serum, and epicardial fat among patients with aortic stenosis undergoing aortic valve replacement.Scientific reports · 2025Article
- Association of preoperative systemic inflammation with postoperative conduction block in TAVI patients.Frontiers in cardiovascular medicine · 2025Article
- Non-rheumatic calcific aortic valve disease in China: findings from the Global Burden of Disease study 2021.Frontiers in cardiovascular medicine · 2025Article
- Sex-Related Differences in the Pathophysiology, Cardiac Imaging, and Clinical Outcomes of Aortic Stenosis: A Narrative Review.Journal of clinical medicine · 2024Review
- Global, regional, and national time trends in disability-adjusted life years, mortality, and variable risk factors of non-rheumatic calcified aortic valve disease, 1990-2019: an age-period-cohort analysis of the Global Burden of Disease 2019 study.Journal of thoracic disease · 2023Article
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
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Abstract
Aortic stenosis is the most common valvular heart disease affecting the elderly. While most patients have a prolonged asymptomatic phase, the development of symptoms ushers in a phase clinical deterioration that often leads to sudden death without an intervention. Treatment of aortic stenosis with valve replacement often relieves the symptoms but still leaves behind a remodeled left ventricle which may not recover. Understanding the pathophysiology of aortic stenosis and realizing that the disease process may be a more active biological entity rather than a passive degenerative process will help us prevent it. This review serves to summarize the latest literature on the pathophysiology of aortic stenosis in the elderly.
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Registered trials
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