Evidence map›Paper›PMID 36588628›Full record

ArticleCase reports in endocrinology2022

BYPASS-OMA: Hypoglycemic Hyperinsulinemic Nesidioblastosis after Gastric Bypass Surgery-A Case Report and Review of the Literature.

Jessica Cao, Cindy Kim, Thatcher Huynh, Amanda Frugoli, Heidi Henson, Vera Valdez, Tricia Westhoff-Pankratz

Open access · goldAbstract readCase Reports
In one paragraph

Article in Case reports in endocrinology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Jessica CaoWestern University of Health Sciences, Community Memorial Hospital, Department of Internal Medicine, 147 N Brent St, Ventura, California 93003, USA.ORCID https://orcid.org/0000-0003-0979-1307
Cindy KimWestern University of Health Sciences, Community Memorial Hospital, Department of Internal Medicine, 147 N Brent St, Ventura, California 93003, USA.ORCID https://orcid.org/0000-0003-1900-6456
Thatcher HuynhCommunity Memorial Hospital, Department of Graduate Medical Education, Department of Internal Medicine, 147 N Brent St, Ventura, California 93003, USA.ORCID https://orcid.org/0000-0003-1696-7518
Amanda FrugoliCommunity Memorial Hospital, Department of Graduate Medical Education, Department of Internal Medicine, 147 N Brent St, Ventura, California 93003, USA.ORCID https://orcid.org/0000-0002-4846-8855
Heidi HensonCommunity Memorial Hospital, Department of Graduate Medical Education, Department of Internal Medicine, 147 N Brent St, Ventura, California 93003, USA.
Vera ValdezCommunity Memorial Hospital, Department of Graduate Medical Education, Department of Internal Medicine, 147 N Brent St, Ventura, California 93003, USA.ORCID https://orcid.org/0000-0001-9632-4402
Tricia Westhoff-PankratzCommunity Memorial Hospital, Department of Internal Medicine, Department of Endocrinology, 147 N Brent St, California 93003, USA.ORCID https://orcid.org/0000-0003-3418-6213
Memorial Hospital of South Bend · USMemorial Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This rare case vignette describes hypoglycemic, hyperinsulinemic nesidioblastosis in a female patient with prior Roux-en-Y gastric bypass. The patient presented with severe symptomatic hypoglycemia resistant to IV dextrose and diazoxide, requiring surgical resection. Traditional imaging found nonspecific findings, and biochemical analysis was inconsistent with insulinoma. A gallium-68 dotatate PET scan was utilized to successfully localize the tumor in the distal pancreas. She underwent laparoscopic resection of the distal pancreatic lesion with resolution of her symptoms and return to euglycemia. The histological evaluation confirmed the diagnosis of nesidioblastosis. Nesidioblastosis is a rare complication of bariatric surgery that may be more clinically relevant with rising prevalence of obesity. Diagnosis with conventional imaging modalities may be challenging; however, the dotatate PET scan may have high utility in detecting lesions. It is essential for clinicians to consider nesidioblastosis in the differential diagnosis of hyperinsulinemic hypoglycemic conditions and recognize there may be a link with increasing rates of bariatric surgery.

Identifiers

PMID36588628
PMCPMC9800099
OpenAlexW4312090006

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.