Evidence map›Paper›PMID 36588564›Full record

ArticleFrontiers in cardiovascular medicine2022

Rapid cardiovascular aging following allogeneic hematopoietic cell transplantation for hematological malignancy.

Hayley T Dillon, Stephen Foulkes, Yuki A Horne-Okano, David Kliman, David W Dunstan, Robin M Daly, Steve F Fraser, Sharon Avery, Bronwyn A Kingwell, Andre La Gerche and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cardiovascular medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Hayley T DillonClinical Research Domain, Baker Heart and Diabetes Institute, Melbourne, VIC, Australia.
Stephen FoulkesClinical Research Domain, Baker Heart and Diabetes Institute, Melbourne, VIC, Australia.
Yuki A Horne-OkanoClinical Research Domain, Baker Heart and Diabetes Institute, Melbourne, VIC, Australia.
David KlimanMalignant Haematology and Stem Cell Transplantation Service, Alfred Hospital, Melbourne, VIC, Australia.
David W DunstanClinical Research Domain, Baker Heart and Diabetes Institute, Melbourne, VIC, Australia.
Robin M DalyInstitute of Physical Activity and Nutrition, School of Exercise and Nutrition Sciences, Deakin University, Geelong, VIC, Australia.
Steve F FraserInstitute of Physical Activity and Nutrition, School of Exercise and Nutrition Sciences, Deakin University, Geelong, VIC, Australia.
Sharon AveryMalignant Haematology and Stem Cell Transplantation Service, Alfred Hospital, Melbourne, VIC, Australia.
Bronwyn A KingwellClinical Research Domain, Baker Heart and Diabetes Institute, Melbourne, VIC, Australia.
Andre La GercheClinical Research Domain, Baker Heart and Diabetes Institute, Melbourne, VIC, Australia.
Erin J HowdenClinical Research Domain, Baker Heart and Diabetes Institute, Melbourne, VIC, Australia.
Baker Heart and Diabetes Institute · AUDeakin University · AUThe Alfred Hospital · AUCSL (Australia) · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Allogeneic hematopoietic cell transplantation (allo-HCT) offers a potential cure for high-risk hematological malignancy; however, long-term survivors experience increased cardiovascular morbidity and mortality. It is unclear how allo-HCT impacts cardiovascular function in the short-term. Thus, this 3-month prospective study sought to evaluate the short-term cardiovascular impact of allo-HCT in hematological cancer patients, compared to an age-matched non-cancer control group. Methods: Before and ~3-months following allo-HCT, 17 hematological cancer patients (45 ± 18 years) underwent cardiopulmonary exercise testing to quantify peak oxygen uptake (VO Results: Conclusion: In summary, allo-HCT severely impairs VO

Indexed as

cardiac functioncardiopulmonary fitnesscardiotoxicitycardiovascular diseaseexercise testinghematological cancer

Identifiers

PMID36588564
PMCPMC9797839
OpenAlexW4311506408

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.