Evidence map›Paper›PMID 36588423›Full record

ArticleBritish journal of sports medicine2022

Healthspan and chronic disease burden among young adult and middle-aged male former American-style professional football players.

Rachel Grashow, Taylor Valencia Shaffer-Pancyzk, Inana Dairi, Hang Lee, Dean Marengi, Jillian Baker, Marc G Weisskopf, Frank E Speizer, Alicia J Whittington, Herman A Taylor and 6 more

Open access · hybridAbstract read
In one paragraph

Article in British journal of sports medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.3field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 7 institutions in 2 countries.

Rachel GrashowDepartment of Environmental Health, Harvard University T H Chan School of Public Health, Boston, Massachusetts, USA rgrashow@hsph.harvard.edu.ORCID http://orcid.org/0000-0001-6961-0243
Taylor Valencia Shaffer-PancyzkParkinson's Disease and Movement Disorders Center, Northwestern University, Evanston, Illinois, USA.
Inana DairiFootball Players Health Study at Harvard University, Harvard Medical School, Boston, Massachusetts, USA.
Hang LeeMassachusetts General Hospital Biostatistics Center, Harvard Medical School, Boston, Massachusetts, USA.
Dean MarengiDepartment of Environmental Health, Harvard University T H Chan School of Public Health, Boston, Massachusetts, USA.
Jillian BakerDepartment of Epidemiology, University of Michigan, Ann Arbor, Michigan, USA.
Marc G WeisskopfDepartment of Environmental Health, Harvard University T H Chan School of Public Health, Boston, Massachusetts, USA.
Frank E SpeizerFootball Players Health Study at Harvard University, Harvard Medical School, Boston, Massachusetts, USA.
Alicia J WhittingtonFootball Players Health Study at Harvard University, Harvard Medical School, Boston, Massachusetts, USA.
Herman A TaylorFootball Players Health Study at Harvard University, Harvard Medical School, Boston, Massachusetts, USA.
Dylan KeatingDepartment of Environmental Health, Boston University School of Public Health, Boston, Massachusetts, USA.
Adam TenfordeDepartment of Physical Medicine and Rehabilitation, Spaulding Rehabilitation Hospital, Boston, Massachusetts, USA.
James Sawalla GusehCardiovascular Performance Program, Massachusetts General Hospital, Boston, Massachusetts, USA.
Meagan M WasfyCardiovascular Performance Program, Massachusetts General Hospital, Boston, Massachusetts, USA.ORCID http://orcid.org/0000-0003-0398-0481
Ross ZafonteDepartment of Physical Medicine and Rehabilitation, Spaulding Rehabilitation Hospital, Massachusetts General Hospital, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Aaron BaggishCardiovascular Performance Program, Massachusetts General Hospital, Boston, Massachusetts, USA.
Harvard University · USMassachusetts General Hospital · USBrigham and Women's Hospital · USBoston University · USNorthwestern University · USSpaulding Rehabilitation Hospital · USUniversity of Michigan · US

Funding

The Harvard Clinical and Translational Science CenterUL1TR002541 · NCATS · HARVARD MEDICAL SCHOOL · PI NADLER, LEE MARSHALL · 2018 to 2022
$93.0M
NCATS NIH HHS UL1 TR002541
6 · The paper itself

Abstract

objectiveTo examine the relationships between age, healthspan and chronic illness among former professional American-style football (ASF) players.

methodsWe compared age-specific race-standardised and body mass index-standardised prevalence ratios of arthritis, dementia/Alzheimer's disease, hypertension and diabetes among early adult and middle-aged (range 25-59 years) male former professional ASF players (n=2864) with a comparator cohort from the National Health and Nutrition Examination Survey and National Health Interview Survey, two representative samples of the US general population. Age was stratified into 25-29, 30-39, 40-49 and 50-59 years.

resultsArthritis and dementia/Alzheimer's disease were more prevalent among ASF players across all study age ranges (all p<0.001). In contrast, hypertension and diabetes were more prevalent among ASF players in the youngest age stratum only (p<0.001 and p<0.01, respectively). ASF players were less likely to demonstrate intact healthspan (ie, absence of chronic disease) than the general population across all age ranges.

conclusionThese data suggest the emergence of a maladaptive early ageing phenotype among former professional ASF players characterised by premature burden of chronic disease and reduced healthspan. Additional study is needed to investigate these findings and their impact on morbidity and mortality in former ASF players and other athlete groups.

Indexed as

cardiovascular diseaseschronicfootballosteoarthritis

Identifiers

PMID36588423
PMCPMC9887383
OpenAlexW4311844938

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.