Evidence map›Paper›PMID 36588328›Full record

ArticlePhotochemistry and photobiology2023

Nanoformulation of Lipophilic Osmium Photosensitizers in Liposomes and Micelles as a General Strategy for Improving Reproducibility and Reducing Quenching

Elizabeth T Papish

Abstract read
In one paragraph

Article in Photochemistry and photobiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Elizabeth T PapishDepartment of Chemistry and Biochemistry, The University of Alabama, Tuscaloosa, AL.ORCID 0000-0002-7937-8019

Funding

Singlet oxygen formation vs. photodissociation for protic ruthenium anticancer compounds: The oxygenated substituent determines the mode of action and the cytotoxicityR15GM132803 · NIGMS · UNIVERSITY OF ALABAMA IN TUSCALOOSA · PI PAPISH, ELIZABETH TABITHA · 2019 to 2022
$844k
NIGMS NIH HHS R15 GM132803
6 · The paper itself

Abstract

Nanoformulation of an osmium photosensitizer within liposomes and micelles is used to improve the water-solubility of this highly lipophilic molecule. This highlight report describes a recent paper by Cameron, Obaid and McFarland on this topic and discusses the context for this report. Nanoformulation has been explored as a strategy before, but this represents the first usage of this strategy with highly potent metal-based photosensitizers having phototherapeutic indices (PIs) in excess of 10

Indexed as

LiposomesPhotochemotherapyMicellesOsmiumPhotosensitizing AgentsReproducibility of ResultsLiposomesMicellesOsmiumPhotosensitizing Agents

Identifiers

PMID36588328
PMCPMC10197950

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.