Evidence map›Paper›PMID 36588140›Full record

SynthesisNeuropsychology review2024

Neuropsychological Changes in Isolated REM Sleep Behavior Disorder: A Systematic Review and Meta-analysis of Cross-sectional and Longitudinal Studies.

Caterina Leitner, Giada D'Este, Laura Verga, Shady Rahayel, Samantha Mombelli, Marco Sforza, Francesca Casoni, Marco Zucconi, Luigi Ferini-Strambi, Andrea Galbiati

Abstract readMeta-AnalysisSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Neuropsychology review, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
5.1field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 29 citations in OpenAlex.

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  14. Cortical and subcortical morphometric changes and their relation to cognitive impairment in isolated REM sleep behavior disorder.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 3 countries.

Caterina Leitner"Vita-Salute" San Raffaele University, Milan, Italy.ORCID 0000-0001-7179-1004
Giada D'Este"Vita-Salute" San Raffaele University, Milan, Italy.ORCID 0000-0002-1542-7467
Laura VergaComparative Bioacoustics Group, Max Planck Institute for Psycholinguistics, Nijmegen, The Netherlands.ORCID 0000-0001-8957-5027
Shady RahayelThe Neuro (Montreal Neurological Institute-Hospital), McGill University, Montreal, QC, Canada.ORCID 0000-0001-5786-3278
Samantha MombelliDepartment of Clinical Neurosciences, Neurology - Sleep Disorders Center, IRCCS San Raffaele Scientific Institute, Via Stamira d'Ancona, 20, 20127, Milan, Italy.ORCID 0000-0002-5406-8620
Marco Sforza"Vita-Salute" San Raffaele University, Milan, Italy.ORCID 0000-0002-0755-8758
Francesca CasoniDepartment of Clinical Neurosciences, Neurology - Sleep Disorders Center, IRCCS San Raffaele Scientific Institute, Via Stamira d'Ancona, 20, 20127, Milan, Italy.ORCID 0000-0002-5086-8014
Marco ZucconiDepartment of Clinical Neurosciences, Neurology - Sleep Disorders Center, IRCCS San Raffaele Scientific Institute, Via Stamira d'Ancona, 20, 20127, Milan, Italy.ORCID 0000-0002-4034-476X
Luigi Ferini-Strambi"Vita-Salute" San Raffaele University, Milan, Italy.ORCID 0000-0003-2867-5424
Andrea Galbiati"Vita-Salute" San Raffaele University, Milan, Italy. andrea.galbiati.unisr@gmail.com.ORCID 0000-0001-8132-1399
Vita-Salute San Raffaele University · ITMaastricht University · NLMontreal Neurological Institute and Hospital · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this meta-analysis is twofold: (a) to assess cognitive impairments in isolated rapid eye movement (REM) sleep behavior disorder (iRBD) patients compared to healthy controls (HC); (b) to quantitatively estimate the risk of developing a neurodegenerative disease in iRBD patients according to baseline cognitive assessment. To address the first aim, cross-sectional studies including polysomnography-confirmed iRBD patients, HC, and reporting neuropsychological testing were included. To address the second aim, longitudinal studies including polysomnography-confirmed iRBD patients, reporting baseline neuropsychological testing for converted and still isolated patients separately were included. The literature search was conducted based on PRISMA guidelines and the protocol was registered at PROSPERO (CRD42021253427). Cross-sectional and longitudinal studies were searched from PubMed, Web of Science, Scopus, and Embase databases. Publication bias and statistical heterogeneity were assessed respectively by funnel plot asymmetry and using I

Indexed as

Cognitive DysfunctionNeurodegenerative DiseasesREM Sleep Behavior DisorderCross-Sectional StudiesHumansLongitudinal StudiesCognitive functionsMeta-analysisMild cognitive impairmentNeuropsychological assessmentREM sleep behavior disorderSynucleinopathies

Identifiers

PMID36588140
OpenAlexW4313380608

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.