Evidence map›Paper›PMID 36587979›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2023

In Vivo Precision Evaluation of Lymphatic Function by SWIR Luminescence Imaging with PbS Quantum Dots.

Xinxian Meng, Huizhu Li, Yuzhou Chen, Liman Sai, Sijia Feng, Ke Li, Wenjing Xi, Yunxia Li, Nguyen T K Thanh, Yueming Wang and 6 more

Open access · goldAbstract read
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Article
  3. Regenerative biomaterials · 2025
    Article
  4. Article
  5. A Review of in vivo Toxicity of Quantum Dots in Animal Models.International journal of nanomedicine · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 6 institutions in 3 countries.

Xinxian MengDepartment of Plastic and Reconstructive Surgery, Shanghai Ninth People's Hospital, School of Medicine, Shanghai Jiao Tong University, 639 Zhizaoju Rd., Shanghai, 200011, P. R. China.
Huizhu LiSports Medicine Institute of Fudan University, Department of Sports Medicine, Huashan Hospital, Fudan University, Shanghai, 200040, P. R. China.
Yuzhou ChenSports Medicine Institute of Fudan University, Department of Sports Medicine, Huashan Hospital, Fudan University, Shanghai, 200040, P. R. China.
Liman SaiDepartment of Physics, Shanghai Normal University, Guilin Road 100, Shanghai, 200234, P. R. China.
Sijia FengSports Medicine Institute of Fudan University, Department of Sports Medicine, Huashan Hospital, Fudan University, Shanghai, 200040, P. R. China.
Ke LiDepartment of Plastic and Reconstructive Surgery, Shanghai Ninth People's Hospital, School of Medicine, Shanghai Jiao Tong University, 639 Zhizaoju Rd., Shanghai, 200011, P. R. China.
Wenjing XiDepartment of Plastic and Reconstructive Surgery, Shanghai Ninth People's Hospital, School of Medicine, Shanghai Jiao Tong University, 639 Zhizaoju Rd., Shanghai, 200011, P. R. China.
Yunxia LiSports Medicine Institute of Fudan University, Department of Sports Medicine, Huashan Hospital, Fudan University, Shanghai, 200040, P. R. China.
Nguyen T K ThanhBiophysics Group, Department of Physics and Astronomy, University College London, Gower Street, London, WC1E 6BT, UK.
Yueming WangDepartment of Anatomy and Physiology, School of Medicine, Shanghai Jiao Tong University, Shanghai, 200025, P. R. China.
Yan WoDepartment of Anatomy and Physiology, School of Medicine, Shanghai Jiao Tong University, Shanghai, 200025, P. R. China.
Xing YangDepartment of orthopedics, Affiliated Suzhou Hospital of Nanjing Medical University, Suzhou, 215500, P. R. China.
Yuefeng HaoDepartment of orthopedics, Affiliated Suzhou Hospital of Nanjing Medical University, Suzhou, 215500, P. R. China.
Yixin ZhangDepartment of Plastic and Reconstructive Surgery, Shanghai Ninth People's Hospital, School of Medicine, Shanghai Jiao Tong University, 639 Zhizaoju Rd., Shanghai, 200011, P. R. China.
Jun ChenSports Medicine Institute of Fudan University, Department of Sports Medicine, Huashan Hospital, Fudan University, Shanghai, 200040, P. R. China.ORCID 0000-0003-4573-801X
Shaoqing FengDepartment of Plastic and Reconstructive Surgery, Shanghai Ninth People's Hospital, School of Medicine, Shanghai Jiao Tong University, 639 Zhizaoju Rd., Shanghai, 200011, P. R. China.
Shanghai Jiao Tong University · CNFudan University · CNShanghai Ninth People's Hospital · CNHuashan Hospital · CNShanghai Normal University · CNSuzhou Municipal Hospital · CN

Funding

Clinical Research Plan of SHDC SHDC2020CR2045BHuashan Hospital Talent Funding Scheme 3030278001Interdisciplinary Program of Shanghai Jiao Tong University YG2019QNB09Medical Engineering Joint Fund of Fudan University YG2022-14National Key R&D Program of China 2021YFA1201303National Natural Science Foundation of China 81772339National Natural Science Foundation of China 81972121National Natural Science Foundation of China 81972129National Natural Science Foundation of China 82011530023National Natural Science Foundation of China 82072521National Natural Science Foundation of China 82111530200National Natural Science Foundation of China 82172222National Natural Science Foundation of China 82172511Research Project of Shanghai Science and Technology Commission 22DZ2204900Sanming Project of Medicine in Shenzhen SZSM201612078Shanghai Municipal Education Commission Gaofeng Clinical Medicine Grant Support 20152227Shanghai Sailing Program 21YF1404100Shanghai Sailing Program 22YF1405200Shanghai Talent Development Funding Scheme 2020080The Introduction Project of Clinical Medicine Expert Team for Suzhou SZYJTD201714The program of Shanghai Municipal Key Clinical Specialty shslczdzk00901
6 · The paper itself

Abstract

Advancements in lymphography technology are essential for comprehensive investigation of the lymphatic system and its function. Here, a shortwave infrared (SWIR) luminescence imaging of lymphatic vessels is proposed in both normal and lymphatic dysfunction in rat models with PbS quantum dots (PbS Qdots). The lymphography with PbS Qdots can clearly and rapidly demonstrate the normal lymphatic morphology in both the tail and hind limb. More importantly, compared to ICG, SWIR luminescence imaging with PbS Qdots can easily identify the dominant lymphatic vessel and node with higher luminescence signal in rats. Moreover, lymphatic pump is identified as segment contracting sections with a size of ≈1 cm in rat by in vivo SWIR lymphograhy, which propose a direct feature for precise evaluation of lymphatic function. Notably, in vivo SWIR luminescence imaging with PbS Qdots also clearly deciphers the in vivo pattern of morphological and function recovery from lymphatic system in rat model. In summary, SWIR luminescence imaging with PbS Qdots can improve the lymphography and thus deepen the understanding of the morphology and structure of the lymphatic system as well as lymphatic function such as lymphatic pump, which will facilitate the diagnosis of lymphatic dysfunction in the future.

Indexed as

Lymphatic VesselsQuantum DotsAnimalsDiagnostic ImagingLuminescenceLymphographyRatslymphatic functionlymphatic systemlymphographyshortwave infrared (SWIR)

Identifiers

PMID36587979
PMCPMC9982568
OpenAlexW4313380765

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.